Evidence map›Paper›PMID 33678099›Full record

ArticleAnnals of medicine2021

Stroke mimics: incidence, aetiology, clinical features and treatment.

Brian H Buck, Naveed Akhtar, Anas Alrohimi, Khurshid Khan, Ashfaq Shuaib

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Annals of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06045455 (The Importance of Multimodal CT Examination in Stroke Mimics Diagnosis), which is not on this map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06045455 recruitingnot on this mapstarted 2023, after this paper: background citation

The Importance of Multimodal CT Examination in Stroke Mimics Diagnosis: a Prospective Observational Multicenter Study

TypeobservationalSponsorUniversity Hospital OstravaRan2023 to 2026Enrolled3,000ConditionsStroke MimicsArmsMultimodal brain CT, Magnetic resonance imaging (MRI)
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.

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  11. Atypical Hypoglycemia-Induced Stroke Mimic: A Case Report and Literature Review.Clinical medicine insights. Endocrinology and diabetes · 2026
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Brian H BuckDepartment of Medicine (Neurology), University of Alberta, Edmonton, Canada.
Naveed AkhtarNeurological Institute, Hamad Medical Corporation, Doha, Qatar.
Anas AlrohimiDepartment of Medicine (Neurology), University of Alberta, Edmonton, Canada.
Khurshid KhanDepartment of Medicine (Neurology), University of Alberta, Edmonton, Canada.
Ashfaq ShuaibDepartment of Medicine (Neurology), University of Alberta, Edmonton, Canada.
University of Alberta · CAHamad Medical Corporation · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mimics account for almost half of hospital admissions for suspected stroke. Stroke mimics may present as a functional (conversion) disorder or may be part of the symptomatology of a neurological or medical disorder. While many underlying conditions can be recognized rapidly by careful assessment, a significant proportion of patients unfortunately still receive thrombolysis and admission to a high-intensity stroke unit with inherent risks and unnecessary costs. Accurate diagnosis is important as recurrent presentations may be common in many disorders. A non-contrast CT is not sufficient to make a diagnosis of acute stroke as the test may be normal very early following an acute stroke. Multi-modal CT or magnetic resonance imaging (MRI) may be helpful to confirm an acute ischaemic stroke and are necessary if stroke mimics are suspected. Treatment in neurological and medical mimics results in prompt resolution of the symptoms. Treatment of functional disorders can be challenging and is often incomplete and requires early psychiatric intervention.

Indexed as

Brain IschemiaHumansIncidenceMagnetic Resonance ImagingStrokeTomography, X-Ray ComputedmimicsMRIrecurrenceStrokeTIA

Identifiers

PMID33678099
PMCPMC7939567
OpenAlexW3134559583

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.