ArticleThe neuroradiology journal2021
Sensitivity and specificity of neuroimaging signs in patients with idiopathic intracranial hypertension.
Article in The neuroradiology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- Inpatient versus outpatient management of bilateral optic nerve head elevation presentation to a tertiary emergency department.BMJ neurology open · 2026Article
- Number of Radiologic Abnormalities Associated with Idiopathic Intracranial Hypertension as a Predictor of the Presence of Pulsatile Tinnitus.Otology & neurotology open · 2025Article
- Optic Nerve Sheath Dilation Is a Possible Marker of CSF Dyshomeostasis in Idiopathic Intracranial Hypertension.Clinical neuroradiology · 2025Article
- Idiopathic intracranial hypertension: Imaging and clinical fundamentals.World journal of radiology · 2024Review
- Magnetic Resonance Imaging Signs of Idiopathic Intracranial Hypertension.JAMA network open · 2024Article
- MRI features of idiopathic intracranial hypertension are not prognostic of visual and headache outcome.The journal of headache and pain · 2023Article
- Article
- Idiopathic intracranial hypertension - a wider spectrum than headaches and blurred vision.The neuroradiology journal · 2022Article
- Is foramen magnum decompression for acquired Chiari I malformation like putting a finger in the dyke? - A simplistic overview of artificial intelligence in assessing critical upstream and downstream etiologies.Journal of craniovertebral junction & spineArticle
- Idiopathic Intracranial Hypertension- The Eyes and Beyond.Annals of Indian Academy of NeurologyArticle
- Characteristics and visual outcomes of idiopathic intracranial hypertension in males in the Saudi population.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe primary role of neuroimaging in idiopathic intracranial hypertension (IIH) is to exclude secondary causes of raised intracranial pressure. Recently, a few imaging markers have been described which may suggest diagnosis of IIH in atypical cases. We carried out this study to assess the prevalence and accuracy of these neuroimaging signs in predicting the diagnosis of IIH.
methodsEighty treatment-naive patients with IIH and 30 controls were recruited as per a predefined criterion. Magnetic resonance imaging (MRI) brain with detailed sella imaging was done in all patients.
resultsThe most common abnormality noted was optic nerve tortuosity in 82.5% of patients, followed by posterior scleral flattening in 80%, perioptic subarachnoid space (SAS) dilatation in 73.8% and partial empty sella in 68.8% of patients. The presence of optic nerve tortuosity was the most sensitive sign on neuroimaging, though the highest specificity was seen for posterior scleral flattening and perioptic SAS dilatation. The presence of more than three neuroimaging features correlated with severity of vision loss.
conclusionIn suggestive clinical scenarios, posterior scleral flattening, perioptic SAS dilatation and optic nerve tortuosity are highly sensitive and specific signs in IIH. This study also highlights the utility of MRI as a valuable tool for prognosis of visual outcome in patients with IIH.
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