Evidence map›Paper›PMID 33677967›Full record

ArticleBioconjugate chemistry2022

Iridium(III) Complex-Loaded Perfluoropropane Nanobubbles for Enhanced Sonodynamic Therapy.

Pinunta Nittayacharn, Eric Abenojar, Massimo La Deda, Loredana Ricciardi, Giuseppe Strangi, Agata A Exner

Open access · greenAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Life at the interface: Engineering bio-nanomaterials through interfacial molecular self-assembly.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
  8. Nanobubble Contrast Enhanced Ultrasound Imaging: A Review.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Pinunta NittayacharnDepartment of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, United States.ORCID 0000-0003-1114-4328
Eric AbenojarDepartment of Radiology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, United States.ORCID 0000-0002-2733-4006
Massimo La DedaDepartment of Chemistry and Chemical Technologies, University of Calabria, 87036 Rende, Cosenza, Italy.ORCID 0000-0002-8611-5575
Loredana RicciardiCNR NANOTEC - Institute of Nanotechnology, UOS Cosenza, 87036 Rende, Cosenza, Italy.
Giuseppe StrangiCNR NANOTEC - Institute of Nanotechnology, UOS Cosenza, 87036 Rende, Cosenza, Italy.
Agata A ExnerDepartment of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, United States.
Case Western Reserve University · USIstituto di Nanotecnologia · IT

Funding

Improved Detection of Prostate Cancer with Nanoparticle-based Ultrasound Contrast Agents Targeted to PSMAR01EB025741 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI James Peter Basilion, Agata A Exner · 2018 to 2026
$4.1M
Drug-Loaded Nanobubbles for Ultrasound Enhanced Delivery to Colon Cancer Liver MetastasisR01EB028144 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI EXNER, AGATA A · 2019 to 2023
$2.3M
Acquisition of a Leica TCS SP5 Confocal Microscope For A Multi-User FacilityS10OD016164 · OD · CASE WESTERN RESERVE UNIVERSITY · PI CONRAD, PATRICIA A · 2013 to 2013
$597k
NIBIB NIH HHS R01 EB025741NIBIB NIH HHS R01 EB028144NIH HHS S10 OD016164
6 · The paper itself

Abstract

Sonodynamic therapy (SDT) is a novel promising approach for the minimally invasive treatment of cancer derived from photodynamic therapy (PDT). In this study, we have explored an effective sonosensitizer for SDT by loading the iridium(III) complex [Ir(

Indexed as

IridiumOvarian NeoplasmsApoptosisCell Line, TumorFemaleFluorocarbonsHumansReactive Oxygen SpeciesFluorocarbonsIridiumperflutrenReactive Oxygen Species

Identifiers

PMID33677967
PMCPMC10108504
OpenAlexW3135652125

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.