ArticleEpidemiology and health2021
Comorbidity network analysis related to obesity in middle-aged and older adults: findings from Korean population-based survey data.
Article in Epidemiology and health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 44 citations in OpenAlex.
- Racial Disparities and Comorbidities: Network Analysis of Maternal Outcomes in Alabama.Journal of racial and ethnic health disparities · 2026Article
- Estimating the association and timing of occurrence between obesity and related comorbidity outcomes in a real-world setting: A cohort study in the United States.Clinical obesity · 2025Article
- Exploring population and sex-specific disease trajectories for multimorbidities among individuals with overweight or obesity: A retrospective cohort study in UK biobank.Diabetes, obesity & metabolism · 2025Article
- Risk factors for pupil changes in patients with diabetic retinopathy and cataract after phacoemulsification with intraocular lens implantation.BMC ophthalmology · 2025Observational
- Multimorbidity patterns of mental disorders and physical diseases of adults in northeast China: a cross-sectional network analysis.Epidemiology and psychiatric sciences · 2025Article
- BMI trajectories, associations with outcomes and predictors in elderly gastric cancer patients undergoing radical gastrectomy: a prospective longitudinal observation study.Journal of cancer survivorship : research and practice · 2025Observational
- Treatment options for heart failure in individuals with overweight or obesity: a review.Future cardiology · 2025Review
- Exploring comorbidity networks in mild traumatic brain injury subjects through graph theory: a traumatic brain injury model systems study.BMC neurology · 2025Article
- Perceptions of Obesity Among Healthcare Professionals and Policy Makers in 2023: Results of the Global OPEN Survey.Obesity science & practice · 2025Article
- Comparison of nutrients and ultra-processed food consumption between different phenotypes defined by abdominal obesity and sarcopenia.Frontiers in nutrition · 2025Article
- Comorbidity patterns and implications for disease control: a network analysis of medical records from Shanghai, China.Frontiers in public health · 2025Article
- Identification of optimal cutoffs for obesity and lipid-related indices in screening activities of daily living disability in Chinese middle-aged and elderly adults.Frontiers in nutrition · 2025Article
- Trends in prevalence of multimorbidity for chronic diseases in China: serial cross-sectional surveys from 2009 to 2018.The journal of nutrition, health & aging · 2024Article
- Choices of measures of association affect the visualisation and composition of the multimorbidity networks.BMC medical research methodology · 2024Article
- Interaction between depressive symptoms and obesity-related anthropometric measures on multimorbidity among community-dwelling older adults: evidence from India.BMC public health · 2024Article
- Chronic disease and multimorbidity in the Chinese older adults' population and their impact on daily living ability: a cross-sectional study of the Chinese Longitudinal Healthy Longevity Survey (CLHLS).Archives of public health = Archives belges de sante publique · 2024Article
- Comorbidity increases the risk of pulmonary tuberculosis: a nested case-control study using multi-source big data.BMC pulmonary medicine · 2024Article
- Progression and trajectory network of age-related functional impairments and their combined associations with mortality.iScience · 2023Article
- Factors associated with the combination of general and abdominal obesity in middle-aged and older Korean women: a cross-sectional study.Osong public health and research perspectives · 2023Article
- The impact of obesity: a narrative review.Singapore medical journal · 2023Review
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2 authors at 1 institution in 1 country.
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Abstract
objectivesWe conducted a comorbidity network analysis using data from the seventh Korea National Health and Nutrition Examination Survey to systematically quantify obesity-related comorbidities.
methodsThe study included 11,712 subjects aged 45 to 80 (5,075 male and 6,637 female). A prevalent disease was defined as a specific disease for which a subject had been diagnosed by a doctor and was being treated. Comorbidity network analysis was performed for diseases with a prevalence of 1% or more, including overweight and obesity. We estimated the observed-to-expected ratio of all possible disease pairs with comorbidity strength and visualized the network of obesity-related comorbidities.
resultsIn subjects over 45 years old, 37.3% of people had a body mass index over 25.0 kg/m2. The most common prevalent disease was hypertension (42.3%), followed by dyslipidemia (17.4%) and diabetes (17.0%). Overweight and obese subjects were 2.1 times (95% confidence interval, 1.9 to 2.3) more likely to have a comorbidity (i.e., 2 or more diseases) than normal-weight subjects. Metabolic diseases such as hypertension, dyslipidemia, diabetes, and osteoarthritis were directly associated with overweight and obesity. The probability of coexistence for each of those 4 diseases was 1.3 times higher than expected. In addition, hypertension and dyslipidemia frequently coexisted in overweight and obese female along with other diseases. In obese male, dyslipidemia and diabetes were the major diseases in the comorbidity network.
conclusionsOur results provide evidence justifying the management of metabolic components in obese individuals. In addition, our results will help prioritize interventions for comorbidity reduction as a public health goal.
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