ReviewArchives of microbiology2021
Bioprospecting of endophytic microorganisms for bioactive compounds of therapeutic importance.
Review in Archives of microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Endophytic Fungi from WildJournal of fungi (Basel, Switzerland) · 2026Article
- A Promising Strain for Wheat Growth Promotion and Antifungal Activity Against Fungal Phytopathogens:Microorganisms · 2026Article
- Endophytic bacteria and fungi as a source of polysaccharides: production and characterization techniques.Frontiers in microbiology · 2026Review
- First report and diversity analysis of endophytic fungi associated with Ulva sp. from Iran.Scientific reports · 2025Article
- Recent Advances and Developments in Bacterial Endophyte Identification and Application: A 20-Year Landscape Review.Plants (Basel, Switzerland) · 2025Review
- Production, characterization, and antifungal action of a biosurfactant obtained from diazotrophic Paenibacillus sp.World journal of microbiology & biotechnology · 2025Article
- Article
- In Vitro and In Vivo Antitumor Activity of a Chloroform Partition fromPlants (Basel, Switzerland) · 2025Article
- IMA fungus · 2025Review
- Metabolomic profiling and 16 S rRNA metabarcoding of endophytes of two Aloe species revealed diverse metabolites.AMB Express · 2024Article
- Isolation, identification, and biological characterization of bacterial endophytes isolated from Gunnera perpensa L.FEMS microbiology letters · 2024Article
- Current Scenario and Future Prospects of Endophytic Microbes: Promising Candidates for Abiotic and Biotic Stress Management for Agricultural and Environmental Sustainability.Microbial ecology · 2023Review
- A computational overview of integrase strand transfer inhibitors (INSTIs) against emerging and evolving drug-resistant HIV-1 integrase mutants.Archives of microbiology · 2023Review
- Epigenetic manipulation for secondary metabolite activation in endophytic fungi: current progress and future directions.Mycology · 2023Review
- Contribution of endophytes towards improving plant bioactive metabolites: a rescue option against red-taping of medicinal plants.Frontiers in plant science · 2023Review
- Characteristics of endophytic bacteria and active ingredients in the Eucommiae cortex from different origins.Frontiers in microbiology · 2023Article
- Exploring the Promise of Endophytic Fungi: A Review of Novel Antimicrobial Compounds.Microorganisms · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Presently, several drug discovery investigations on therapeutic management of human health are aimed at bioprospecting for microorganisms, especially endophytic microbes of biotechnological importance. This review investigates the benefits of endophytes, especially in producing bioactive compounds useful in modern medicine by systematically reviewing published data from 12 databases. Only experimental studies investigating either or both bacterial and fungal endophytes and within the scope of this review were selected. The published data from the last 2 decades (2000-2019) revealed diverse endophytes associated with different plants produce a broad spectrum of bioactive compounds with therapeutic benefits. Notably, antibacterial, followed by anticancer and antifungal activities, were mostly reported. Only three studies investigated the anti-plasmodial activity. The variation observed in the synthesis of bioactive compounds amongst endophytes varied with host type, endophyte species, and cultivation medium. Fungal endophytes were more investigated than bacterial endophytes, with both endophytes having species diversity amongst literature. The endophytes were predominantly from medicinal plants and belonged to either Ascomycota (fungi) or Proteobacteria and Firmicutes (bacteria). This review presents excellent prospects of harnessing endophytes and their unique bioactive compounds in developing novel and effective compounds of medicinal importance.
Indexed as
Identifiers
33677637What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.