ArticleThe journal of allergy and clinical immunology. In practice2021
Multivariate Association of Child Depression and Anxiety with Asthma Outcomes.
Article in The journal of allergy and clinical immunology. In practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05633823 (The Effect of Mobile Application Game Training Designed for Children With Asthma on Asthma Management), which is not on this map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Mobile Application Game Training Designed for Children With Asthma on Asthma Management
Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Mental Health in Eosinophilic Gastrointestinal Disorders: A Work Group Report of the AAAAI Eosinophilic Gastrointestinal Disorders Committee.The journal of allergy and clinical immunology. In practice · 2026Article
- Documented Nicotine, Cannabis, and Co-Use Are Associated With More Intensive Emergency Department Care for Adolescent Asthma Exacerbations.Journal of the American College of Emergency Physicians open · 2026Article
- Assessing the comorbidity between asthma and depression through polygenic risk scoring and time-to-event models.BMC medicine · 2026Article
- Article
- Burden and Factors Associated with Depression and Anxiety Disorders in Pediatric Asthma: A Cross-Sectional Study.Avicenna journal of medicine · 2025Article
- A multi-omics and mediation-based genetic screening approach identifies STX4 as a key link between epigenetic regulation, immune cells, and childhood asthma.Clinical epigenetics · 2025Article
- The Association of Mental Health, Asthma Control and Acute Care Visits Among Rural Adolescents with Poorly Controlled Asthma.The Journal of school nursing : the official publication of the National Association of School Nurses · 2025Article
- The COVID-19 pandemic and asthma management: a family caregiver perspective.The Journal of asthma : official journal of the Association for the Care of Asthma · 2025Article
- Association between higher morning preference and better health-related quality of life in asthma.The journal of allergy and clinical immunology. Global · 2025Article
- Caregivers' burden and its influencing factors among parents of children with asthma and comorbidities: a cross-sectional study.Frontiers in public health · 2025Article
- Airway sensory systems: breathing new life into microbiota-brain communication.Frontiers in cellular neuroscience · 2025Review
- Pediatric pulmonology 2023 year in review: Asthma.Pediatric pulmonology · 2025Review
- The impact of asthma education grounded in virtual reality technology upon the quality of life of pediatric patients with bronchial asthma.Frontiers in pediatrics · 2025Article
- Associations between psychosocial stress, child's anxiety, and lung function in mid-childhood.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024Article
- Unveiling the interoception impairment in various major depressive disorder stages.CNS neuroscience & therapeutics · 2024Article
- Proteomic analysis reveals potential therapeutic targets for childhood asthma through Mendelian randomization.Clinical and translational allergy · 2024Article
- Depressive symptoms are related to asthma control but not self-management among rural adolescents.Frontiers in allergy · 2023Article
- Paediatric asthma and non-allergic comorbidities: A review of current risk and proposed mechanisms.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022Review
- Psychometric validation of the Chinese version of the Adolescent Asthma Self-Efficacy Questionnaire.Frontiers in psychology · 2022Article
- Associations of asthma self-management and mental health in adolescents: A scoping review.Respiratory medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPediatric asthma is associated with increased health services utilization, missed school days, and diminished quality of life. Children with asthma also report more frequent depressive and anxiety symptoms than children without asthma, which may further worsen asthma outcomes.
objectiveThe current study investigated the relationship between depressive and anxiety symptoms and 4 asthma outcomes (asthma control, asthma severity, lung function, and asthma-related quality of life) in children (N = 205) with moderate to severe persistent asthma.
methodsThe data were analyzed using a canonical correlation analysis, a multivariate framework that allows examination of all variables of interest in the same model.
resultsWe found a statistically significant relationship between symptoms of depression and anxiety and asthma outcomes (1 - Λ = .372; P < .001). A large effect size suggests that 37.2% of variance is shared between depression and anxiety symptoms and 4 asthma outcomes (particularly asthma control and asthma-related quality of life) in the overall sample. Among girls (vs. boys), asthma control (measured by the Asthma Control Test) emerged as a stronger contributor to asthma outcomes compared with boys.
conclusionsThese results suggest that psychiatric symptoms, especially anxiety, are associated with poor asthma-related quality of life, and more negative perception of asthma control in girls compared with boys (with no observed sex difference in physiological lung function). Clinicians should consider incorporating questions about psychiatric symptoms as part of routine asthma management, and focus patient education on unique differences in which boys and girls perceive their asthma symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.