Evidence map›Paper›PMID 33676900›Full record

ArticleJournal of geriatric oncology2021

Developing and adapting a mobile health exercise intervention for older patients with myeloid neoplasms: A qualitative study.

Kah Poh Loh, Chandrika Sanapala, Grace Di Giovanni, Heidi D Klepin, Michelle Janelsins, Rebecca Schnall, Eva Culakova, Paula Vertino, Martha Susiarjo, Jason H Mendler and 6 more

Open access · greenAbstract read
In one paragraph

Article in Journal of geriatric oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. User experiences of digital health interventions among older adults with cancer: a systematic review of qualitative data.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Kah Poh LohJames P. Wilmot Cancer Institute, Rochester, NY, USA; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: kahpoh_loh@urmc.rochester.ed.
Chandrika SanapalaJames P. Wilmot Cancer Institute, Rochester, NY, USA. Electronic address: chandrika_sanapala@urmc.rochester.edu.
Grace Di GiovanniJames P. Wilmot Cancer Institute, Rochester, NY, USA. Electronic address: grace_digiovanni@urmc.rochester.edu.
Heidi D KlepinWake Forest Baptist Comprehensive Cancer Center, Medical Center Blvd, Winston-Salem, NC, USA. Electronic address: hklepin@wakehealth.edu.
Michelle JanelsinsJames P. Wilmot Cancer Institute, Rochester, NY, USA; Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: michelle_janelsins@urmc.rochester.edu.
Rebecca SchnallSchool of Nursing, Columbia University, New York, NY, USA. Electronic address: rb897@columbia.edu.
Eva CulakovaJames P. Wilmot Cancer Institute, Rochester, NY, USA; Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: eva_culakova@urmc.rochester.edu.
Paula VertinoJames P. Wilmot Cancer Institute, Rochester, NY, USA; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: paula_vertino@urmc.rochester.edu.
Martha SusiarjoDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: martha_susiarjo@urmc.rochester.edu.
Jason H MendlerJames P. Wilmot Cancer Institute, Rochester, NY, USA; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: jason_mendler@urmc.rochester.edu.
Jane L LiesveldJames P. Wilmot Cancer Institute, Rochester, NY, USA; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: jane_liesveld@urmc.rochester.edu.
Po-Ju LinJames P. Wilmot Cancer Institute, Rochester, NY, USA; Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: po-ju_lin@urmc.rochester.edu.
Richard F DunneJames P. Wilmot Cancer Institute, Rochester, NY, USA; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: richard_dunne@Urmc.rochester.edu.
Ian KlecknerJames P. Wilmot Cancer Institute, Rochester, NY, USA; Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: ian_kleckner@urmc.rochester.edu.
Karen MustianJames P. Wilmot Cancer Institute, Rochester, NY, USA; Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: karen_mustian@urmc.rochester.edu.
Supriya G MohileJames P. Wilmot Cancer Institute, Rochester, NY, USA; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: supriya_mohile@urmc.rochester.edu.
University of Rochester Medical Center · USColumbia University · USWake Forest Baptist Comprehensive Cancer Center

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Geriatric Oncology Research Infrastructure to Improve Clinical CareR33AG059206 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI WILLIAM DALE, Heidi Diana Klepin · 2020 to 2026
$5.1M
Transdisciplinary Research in Energetics and Cancer (TREC) Training GrantR25CA203650 · NCI · YALE UNIVERSITY · PI IRWIN, MELINDA L · 2016 to 2025
$2.9M
A Patient-Oriented Research Program in Geriatric OncologyK24AG056589 · NIA · UNIVERSITY OF ROCHESTER · PI Supriya G. Mohile · 2018 to 2026
$1.5M
The Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy, Inflammation, and Interoceptive Brain CircuitryK07CA221931 · NCI · UNIVERSITY OF ROCHESTER · PI KLECKNER, IAN ROBERT · 2018 to 2022
$795k
A novel mobile health exercise intervention for older patients with myeloid neoplasmsR00CA237744 · NCI · UNIVERSITY OF ROCHESTER · PI LOH, KAH POH · 2021 to 2023
$747k
Geriatric Oncology Research Infrastructure to Improve Clinical CareR21AG059206 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI DALE, WILLIAM, MOHILE, SUPRIYA G. · 2018 to 2019
$478k
A Novel Mobile Health Exercise Intervention for Older Patients with Myeloid NeoplasmsK99CA237744 · NCI · UNIVERSITY OF ROCHESTER · PI LOH, KAH POH · 2019 to 2020
$385k
Mentoring and Research in Self-Management for Health Promotion and Disease PreventionK24NR018621 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SCHNALL, REBECCA · 2019 to 2022
$384k
NCI NIH HHS K07 CA221931NCI NIH HHS K99 CA237744NCI NIH HHS R00 CA237744NCI NIH HHS R25 CA203650NCI NIH HHS UG1 CA189961NIA NIH HHS K24 AG056589NIA NIH HHS R21 AG059206NIA NIH HHS R33 AG059206NINR NIH HHS K24 NR018621
6 · The paper itself

Abstract

introductionOlder patients with myeloid neoplasms (MN) receiving outpatient chemotherapy are at risk of experiencing treatment-related toxicities such as functional decline. A mobile health (mHealth) exercise intervention may ameliorate these toxicities. This qualitative study aimed to inform the design of a mHealth exercise intervention for this population.

methodsThis was a qualitative study of thirteen patients aged ≥60 years receiving hypomethylating agents for MN. EXCAP©® is a home-based walking and progressive resistance exercise program. We combined EXCAP©® with a mobile app; the combination (GO-EXCAP Mobile App) has not been previously tested. A brief verbal description about the intervention was provided to the participants but they did not perform it. Participants were interviewed and inductive thematic analysis was used to analyze the data.

resultsMean age was 71.6 (SD 8.5). Three themes were identified: 1) Perceptions of the intervention feasibility, 2) Ways to leverage the app to deliver the exercise intervention, and 3) Personalized exercise goals. Walking and resistance exercises were perceived to be feasible. Patients were comfortable initiating the intervention in cycle 2 of chemotherapy, with exercise increments occurring from week 2-4 of the cycle. Ways to leverage the app to deliver EXCAP©® include 1) Video feature for exercise demonstration and interactions, and 2) Exercise data and symptom surveys to be communicated to the exercise physiologist and primary oncology team. Preservation of existing function and activity was an important goal to participants.

conclusionsOur findings provide insights about the preferences of older adults with MN for a mHealth exercise intervention.

Indexed as

Mobile ApplicationsNeoplasmsTelemedicineAgedExercise TherapyHumansQualitative ResearchExercise interventionGeriatric hematologyMobile healthMyeloid neoplasms

Identifiers

PMID33676900
PMCPMC8260435
OpenAlexW3135066879

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.