ArticleBiology of sex differences2021
Sex differences in noise-induced hearing loss: a cross-sectional study in China.
Article in Biology of sex differences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Prevalence of Hearing Loss After Open-Heart Surgery: A Systematic Review.Brazilian journal of cardiovascular surgery · 2025Pooled it
- Pooled it
- Annual noise exposure among Malaysian young adults.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Hearing Impairment in Kazakhstan, 2020-2025: Dispensary Registration, Disability Certification, and Cochlear Implantation Response, with Reference to Global Burden of Disease 2021 Modelled Estimates.Audiology research · 2026Article
- Arabic Validation of the Noise-Induced Hearing Loss-Symptoms (NIHL-S) Scale Among Civilians Exposed to Loud Blasts During the 2024 Israeli Invasion of Lebanon.Health science reports · 2026Article
- Prediction of risk of hearing loss by industry noise from cross-sectional and longitudinal data.Communications medicine · 2026Article
- Associations of combined hearing loss and depression with cognitive impairment among older adults: a sex difference analysis based on evidence from CHARLS.BMC public health · 2026Article
- Aging in the Primary Auditory Cortex.Journal of the Association for Research in Otolaryngology : JARO · 2026Review
- Single-Cell Sequencing Reveals Circadian Sensitivity of Noise-Induced Hearing Loss Mediated by Macrophage-Driven NLRP3 Inflammasome Activation.Neuroscience bulletin · 2026Article
- Association between hearing protection device use and noise-induced hearing loss among manufacturing workers in China: a cross-sectional study.Frontiers in public health · 2026Article
- Chronic Loud Noise-Biochemical and Ultrastructural Alterations in Auditory and Limbic Regions of the Rat Brain.BioMed research international · 2026Article
- Global, regional, and national burden of hearing loss from 1990 to 2021: findings from the 2021 global burden of disease study.Annals of medicine · 2025Article
- Sex differences in response to kanamycin-induced ototoxicity in C57BL/6 J mice.Scientific reports · 2025Article
- Associations Between Occupational Noise Exposure, Aging, and Gender and Hearing Loss: A Cross-Sectional Study in China.Audiology research · 2025Article
- miR-145b/AP2B1 Axis Contributes to Noise-induced Sensorineural Hearing Loss In a Male Mouse Model.Cell biochemistry and biophysics · 2025Article
- Evaluation of the Decrease in DPOAE Levels After VEMP Testing in Clinical Patients Referred to the Vertigo Outpatient Clinic.Journal of clinical medicine · 2025Article
- Impacts of hazardous noise levels on hearing loss and tinnitus in dental professionals.Journal of occupational medicine and toxicology (London, England) · 2025Article
- Article
- Awareness of and the relationship between noise-induced hearing loss and the use of personal listening devices in Jazan region, Saudi Arabia.Frontiers in public health · 2025Article
- Global impact of Occupational Noise-Induced Hearing Loss (ONIHL): trends, gender disparities, and future projections: 1990-2036.Frontiers in global women's health · 2025Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundSignificant sex differences exist in hearing physiology, while few human studies have investigated sex differences in noise-induced hearing loss (NIHL), and the sex bias in previous studies resulted in inadequate female data. The study aims to investigate sex differences in the characteristics of NIHL to provide insight into sex-specific risk factors, prevention strategies and treatment for NIHL.
methodsThis cross-sectional study included 2280 industrial noise-exposed shipyard workers (1140 males and 1140 females matched for age, job and employment length) in China. Individual noise exposure levels were measured to calculate the cumulative noise exposure (CNE), and an audiometric test was performed by an experienced technician in a soundproof booth. Sex differences in and influencing factors of low-frequency (LFHL) and high-frequency hearing loss (HFHL) were analyzed using logistic regression models stratified by age and CNE.
resultsAt comparable noise exposure levels and ages, the prevalence of HFHL was significantly higher in males (34.4%) than in females (13.8%), and males had a higher prevalence of HFHL (OR = 4.19, 95% CI 3.18 to 5.52) after adjusting for age, CNE, and other covariates. Sex differences were constant and highly remarkable among subjects aged 30 to 40 years and those with a CNE of 80 to 95 dB(A). Alcohol consumption might be a risk factor for HFHL in females (OR = 3.12, 95% CI 1.10 to 8.89).
conclusionsThis study indicates significant sex differences in NIHL. Males are at higher risk of HFHL than females despite equivalent noise exposure and age. The risk factors for NIHL might be different in males and females.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.