Evidence map›Paper›PMID 33676453›Full record

SynthesisBMC pediatrics2021

Prevalence of problematic feeding in young children born prematurely: a meta-analysis.

Britt Frisk Pados, Rebecca R Hill, Joy T Yamasaki, Jonathan S Litt, Christopher S Lee

Registry-linked trialOpen access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06736743 (Review of Infant Oral Feeding and Skills Study), which is not on this map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06736743 completednot on this mapstarted 2025, after this paper: background citation

Review of Infant Oral Feeding and Skills Study

TypeobservationalSponsorWake Forest University Health SciencesRan2025 to 2026Enrolled108ConditionsNutrition Disorders, Gastrointestinal Disease, Deglutition Disorder, Feeding DifficultiesArmsSMART Tool for Feeding Skill Assessment
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 114 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  5. Article
  6. Examining the Effect of Bottle Angle on Milk Drip Rate Using the Dr. Brown'sThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
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  16. Feeding outcomes of preterm infants discharged with feeding tubes.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  17. Article
  18. Review
  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Britt Frisk PadosBoston College William F. Connell School of Nursing, 140 Commonwealth Avenue, Maloney Hall 268, Chestnut Hill, MA, 02467, USA. britt.pados@bc.edu.ORCID 0000-0002-8016-2370
Rebecca R HillBoston College William F. Connell School of Nursing, 140 Commonwealth Avenue, Maloney Hall 268, Chestnut Hill, MA, 02467, USA.
Joy T YamasakiCHA Hollywood Presbyterian Medical Center, Los Angeles, CA, USA.
Jonathan S LittBeth Israel Deaconess Medical Center, Boston Children's Hospital, Harvard Medical School, Harvard TH Chan School of Public Health, Boston, MA, USA.
Christopher S LeeBoston College William F. Connell School of Nursing, 140 Commonwealth Avenue, Maloney Hall 268, Chestnut Hill, MA, 02467, USA.
Boston College · USBoston Children's Hospital · USTexas Health Dallas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDifficulties related to eating are often reported in children born preterm. The objective of this study was to quantitatively synthesize available data on the prevalence of problematic feeding in children under 4 years of age who were born preterm.

methodsLiterature was identified from PubMed, CINAHL, and PsycInfo. The search was limited to English language and publication years 2000-2020. To be included in the meta-analysis, the article had to report the prevalence of problematic oral feeding within a population of children born prematurely (< 37 weeks' gestation), and the child age at the time of study had to be between full-term corrected age and 48 months. For studies meeting inclusion criteria, the following data were extracted: sample size and subsamples by gestational age and/or child age at time of study; definition of problematic feeding; measures used for assessment of feeding; gestational age at time of birth of sample; child age at time of study; exclusion criteria for the study; and prevalence of problematic feeding. Random-effects meta-analyses were performed to estimate the prevalence of problematic feeding across all studies, by gestational age at birth, and by child age at time of study.

resultsThere were 22 studies that met inclusion criteria. Overall prevalence of problematic feeding (N = 4381) was 42% (95% CI 33-51%). Prevalence was neither significantly different across categories of gestational age nor by child age at the time of study. Few studies used psychometrically-sound assessments of feeding.

conclusionProblematic feeding is highly prevalent in prematurely-born children in the first 4 years of life regardless of degree of prematurity. Healthcare providers of children born preterm should consider screening for problematic feeding throughout early childhood as a potential complication of preterm birth. SYSTEMATIC REVIEW REGISTRATION NUMBER: Not applicable.

Indexed as

Infant, Premature, DiseasesPremature BirthChildChild, PreschoolFemaleGestational AgeHumansInfant, NewbornInfant, PrematurePregnancyPrevalenceBottle feedingBreast feedingChildFeeding and eating disordersFeeding behaviorInfant, premature

Identifiers

PMID33676453
PMCPMC7936467
OpenAlexW3134348212

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.