Evidence map›Paper›PMID 33675821›Full record

ArticleExperimental hematology2021

Hypoxia promotes erythroid differentiation through the development of progenitors and proerythroblasts.

Aditi Bapat, Natascha Schippel, Xiaojian Shi, Paniz Jasbi, Haiwei Gu, Mrinalini Kala, Aparna Sertil, Shalini Sharma

Open access · greenAbstract read
In one paragraph

Article in Experimental hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 44 citations in OpenAlex.

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  17. The Role of Nitric Oxide in Stem Cell Biology.Antioxidants (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Aditi BapatDepartment of Basic Medical Sciences, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ.
Natascha SchippelDepartment of Basic Medical Sciences, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ.
Xiaojian ShiArizona Metabolomics Laboratory, College of Health Solutions, Arizona State University, Scottsdale, AZ.
Paniz JasbiArizona Metabolomics Laboratory, College of Health Solutions, Arizona State University, Scottsdale, AZ.
Haiwei GuArizona Metabolomics Laboratory, College of Health Solutions, Arizona State University, Scottsdale, AZ.
Mrinalini KalaFlow Cytometry Core, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ.
Aparna SertilDepartment of Basic Medical Sciences, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ.
Shalini SharmaDepartment of Basic Medical Sciences, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ. Electronic address: shalinijs@arizona.edu.
University of Arizona · USArizona State University · USUniversity of Phoenix · US

Funding

Mechanisms of Splice Site Selection in Health and DiseaseR01GM127464 · NIGMS · UNIVERSITY OF ARIZONA · PI SHARMA, SHALINI · 2019 to 2023
$1.8M
Examining role of splicing factor mutations in myelodysplastic syndrome (PQ11)R21CA170786 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHARMA, SHALINI · 2012 to 2013
$366k
NCI NIH HHS R21 CA170786NIGMS NIH HHS R01 GM127464
6 · The paper itself

Abstract

Oxygen is a critical noncellular component of the bone marrow microenvironment that plays an important role in the development of hematopoietic cell lineages. In this study, we investigated the impact of low oxygen (hypoxia) on ex vivo myeloerythroid differentiation of human cord blood-derived CD34

Indexed as

ErythropoiesisCell HypoxiaCell ProliferationCells, CulturedErythroblastsErythroid CellsErythroid Precursor CellsHumansMetabolome

Identifiers

PMID33675821
PMCPMC8102433
OpenAlexW3135538753

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.