Evidence map›Paper›PMID 33675766›Full record

ReviewBiophysical journal2021

Principles and practice for SARS-CoV-2 decontamination of N95 masks with UV-C.

Thomas Huber, Olivia Goldman, Alexander E Epstein, Gianna Stella, Thomas P Sakmar

Abstract readReview
In one paragraph

Review in Biophysical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Pollution free UV-C radiation to mitigate COVID-19 transmission.Gondwana research : international geoscience journal · 2023
    Article
  3. Article
  4. Evaluation of the effectiveness of UV-C dose for photoinactivation of SARS-CoV-2 in contaminated N95 respirator, surgical and cotton fabric masks.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Review of the Effect of Continuous Use and Limited Reuse of N95 Respirators on Respirator Fit.Journal of the International Society for Respiratory Protection · 2022
    Article
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas HuberLaboratory of Chemical Biology and Signal Transduction, Tri-Institutional Program in Chemical Biology, The Rockefeller University, New York, New York. Electronic address: hubert@rockefeller.edu.
Olivia GoldmanLaboratory of Neurogenetics and Behavior, The Rockefeller University, New York, New York.
Alexander E EpsteinDavid Rockefeller Graduate Program, The Rockefeller University, New York, New York.
Gianna StellaTri-Institutional Program in Chemical Biology, The Rockefeller University, New York, New York.
Thomas P SakmarLaboratory of Chemical Biology and Signal Transduction, Tri-Institutional Program in Chemical Biology, The Rockefeller University, New York, New York. Electronic address: sakmar@rockefeller.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A mainstay of personal protective equipment during the coronavirus disease 2019 pandemic is the N95 filtering facepiece respirator. N95 respirators are commonly used to protect healthcare workers from respiratory pathogens, including the novel coronavirus severe acute respiratory syndrome coronavirus 2, and are increasingly employed by other frontline workers and the general public. Under routine circumstances, these masks are disposable, single-use items, but extended use and reuse practices have been broadly enacted to alleviate critical supply shortages during the coronavirus disease 2019 pandemic. Although extended-time single use presents a low risk of pathogen transfer, repeated donning and doffing of potentially contaminated masks presents increased risk of pathogen transfer. Therefore, efficient and safe decontamination methods for N95 masks are needed to reduce the risk of reuse and mitigate local supply shortages. Here, we review the available literature concerning use of germicidal ultraviolet-C (UV-C) light to decontaminate N95 masks. We propose a practical method for repeated point-of-use decontamination using commercially available UV-C cross-linker boxes from molecular biology laboratories to expose each side of the mask to 800-1200 mJ/cm

Indexed as

COVID-19SARS-CoV-2DecontaminationEquipment ReuseHumansN95 Respirators

Identifiers

PMID33675766
PMCPMC7929787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.