Evidence map›Paper›PMID 33675761›Full record

ArticleBiophysical journal2021

Characterization of binding kinetics of A

Kirsten S Koretz, Claire E McGraw, Steven Stradley, Ahmed Elbaradei, Noah Malmstadt, Anne S Robinson

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Cholesterol Dependent Activity of the Adenosine AMolecules (Basel, Switzerland) · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kirsten S KoretzDepartment of Chemical and Biomolecular Engineering, Tulane University, New Orleans, Louisiana; Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania.
Claire E McGrawDepartment of Chemical and Biomolecular Engineering, Tulane University, New Orleans, Louisiana.
Steven StradleyDepartment of Chemical and Biomolecular Engineering, Tulane University, New Orleans, Louisiana.
Ahmed ElbaradeiMork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, California.
Noah MalmstadtMork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, California.
Anne S RobinsonDepartment of Chemical and Biomolecular Engineering, Tulane University, New Orleans, Louisiana; Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania. Electronic address: anne.robinson@cmu.edu.
Tulane University · USUniversity of Southern California · US

Funding

This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI SCHMITZ, KARL ROBERT · 2014 to 2024
$26.8M
Effects of lipidomic diversity on GPCRR01GM120351 · NIGMS · UNIVERSITY OF DELAWARE · PI LYMAN, EDWARD RAY · 2017 to 2021
$1.6M
Acquisition of a Surface Plasmon Resonance Biosensor: Enhancing Biomedical (Bio)Molecular Recognition ProjectsS10OD020117 · OD · TULANE UNIVERSITY OF LOUISIANA · PI JAYAWICKRAMARAJAH, JANARTHANAN · 2015 to 2015
$354k
NIGMS NIH HHS P20 GM104316NIGMS NIH HHS R01 GM120351NIH HHS S10 OD020117
6 · The paper itself

Abstract

Because of their surface localization, G protein-coupled receptors (GPCRs) are often pharmaceutical targets as they respond to a variety of extracellular stimuli (e.g., light, hormones, small molecules) that may activate or inhibit a downstream signaling response. The adenosine A

Indexed as

Signal TransductionSurface Plasmon ResonanceGTP-Binding ProteinsHumansKineticsProtein BindingReceptor, Adenosine A2AReceptors, G-Protein-CoupledGTP-Binding ProteinsReceptor, Adenosine A2AReceptors, G-Protein-Coupled

Identifiers

PMID33675761
PMCPMC8204205
OpenAlexW3135321413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.