Evidence map›Paper›PMID 33675535›Full record

ReviewClinical and experimental immunology2021

Immune checkpoint inhibitors and cellular treatment for lymphoma immunotherapy.

F Li, Y Chen, M Pang, P Yang, H Jing

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical and experimental immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Rendering NK Cells Antigen-Specific for the Therapy of Solid Tumours.International journal of molecular sciences · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Observational
  12. Review
  13. Article
  14. Article
  15. Review
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  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

F Li *Department of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing, China.
Y Chen *Department of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing, China.
M PangDepartment of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing, China.
P YangDepartment of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing, China.
H JingDepartment of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing, China.ORCID 0000-0003-4958-2489
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant lymphoma (ML) is a common hematological malignancy with many subtypes. Patients with ML usually undergo traditional treatment failure and become relapsed or refractory (R/R) cases. Recently, immunotherapy, such as immune checkpoint inhibitors (ICIs) and cellular treatment, has gradually emerged and used in clinical trials with encouraging achievements for ML treatment, which exerts anti-tumor activity by blocking the immune evasion of tumor cells and enhancing the attack ability of immune cells. Targets of immune checkpoints include programmed cell death-1 (PD-1), programmed cell death-ligand 1 (PD-L1), cytotoxic T lymphocyte-associated protein 4 (CTLA-4), T cell immunoglobulin and ITIM domain (TIGIT), T cell immunoglobulin-3 (TIM-3) and lymphocyte activation gene 3 (LAG-3). Examples of cellular treatment are chimeric antigen receptor (CAR) T cells, cytokine-induced killer (CIK) cells and natural killer (NK) cells. This review aimed to present the current progress and future prospects of immunotherapy in lymphoma, with the focus upon ICIs and cellular treatment.

Indexed as

AnimalsAntineoplastic Agents, ImmunologicalClinical Trials as TopicHumansImmune Checkpoint InhibitorsImmunotherapyLymphomaAntineoplastic Agents, ImmunologicalImmune Checkpoint Inhibitorscell therapyclinical trialsimmune checkpoint inhibitors (ICIs)immunotherapylymphoma

Identifiers

PMID33675535
PMCPMC8209615
OpenAlexW3135441142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.