Evidence map›Paper›PMID 33675515›Full record

ArticleFood and environmental virology2021

Human Enterovirus Diversity by Next-Generation Sequencing Analysis in Urban Sewage Samples From Buenos Aires Metropolitan Area, Argentina: A Retrospective Study.

A Lizasoain, D Mir, M Victoria, M E Barrios, M D Blanco-Fernández, N Rodríguez-Osorio, S Nates, D Cisterna, V A Mbayed, R Colina

Abstract read
PubMed Publisher
In one paragraph

Article in Food and environmental virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Genetic Characteristics and Phylogeographic Dynamics of Echovirus.Journal of microbiology (Seoul, Korea) · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

A LizasoainLaboratorio de Virología Molecular, Departamento de Ciencias Biológicas, Centro Universitario Regional del Litoral Norte. Universidad de La República, 1350 Gral. Rivera St. Salto, 50000, Salto, Uruguay.ORCID 0000-0001-8062-6916
D MirUnidad de Genómica y Bioinformática. Departamento de Ciencias Biológicas, Centro Universitario Regional del Litoral Norte. Universidad de La República, Salto, Uruguay.
M VictoriaLaboratorio de Virología Molecular, Departamento de Ciencias Biológicas, Centro Universitario Regional del Litoral Norte. Universidad de La República, 1350 Gral. Rivera St. Salto, 50000, Salto, Uruguay.
M E BarriosCátedra de Virología, Instituto de Investigaciones en Bacteriología y Virología Molecular. Facultad de Farmacia Y Bioquímica, Universidad de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
M D Blanco-FernándezCátedra de Virología, Instituto de Investigaciones en Bacteriología y Virología Molecular. Facultad de Farmacia Y Bioquímica, Universidad de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
N Rodríguez-OsorioUnidad de Genómica y Bioinformática. Departamento de Ciencias Biológicas, Centro Universitario Regional del Litoral Norte. Universidad de La República, Salto, Uruguay.
S NatesLaboratorio de Gastroenteritis Virales y Sarampión. Instituto de Virología Dr. J. M. Vanella. Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
D CisternaServicio de Neurovirosis, Departamento de Virología, Instituto Nacional de Enfermedades Infecciosas. Administración Nacional de Laboratorios e Institutos de Salud Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
V A MbayedCátedra de Virología, Instituto de Investigaciones en Bacteriología y Virología Molecular. Facultad de Farmacia Y Bioquímica, Universidad de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
R ColinaLaboratorio de Virología Molecular, Departamento de Ciencias Biológicas, Centro Universitario Regional del Litoral Norte. Universidad de La República, 1350 Gral. Rivera St. Salto, 50000, Salto, Uruguay. rodneycolina1@gmail.com.ORCID 0000-0003-3731-5383
Universidad de la República de Uruguay · UYUniversidad de Buenos Aires · ARAdministración Nacional de Laboratorios e Institutos de Salud · ARUniversidad Nacional de Córdoba · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Enteroviruses (hEVs) are responsible for a wide variety of human diseases. During hEVs infection, virions are excreted in human feces and the fecal-oral route is the primary pathway for person-to-person transmission. Sewage surveillance could help in monitoring hEVs circulation and describing their diversity in a specific population. In this study, sewage samples collected in Buenos Aires Metropolitan Area (Argentina) were retrospectively studied through an amplicon-deep sequencing approach and phylogenetic analyses to characterize hEVs spread. We identified 17 different hEVs types belonging to A, B, and C species. To the best of our knowledge, this is the first report in Buenos Aires for 7 identified hEV-C types. Phylogenetic analyses suggest several introductions of coxsackievirus B4, echovirus 1, and echovirus 9 in the country, along with the national spread reached by some variants. Besides, well-supported monophyletic groups of Argentine, Uruguayan, and Brazilian strains unveiled regional circulation patterns for some variants. These results extend our knowledge about hEVs circulation in Buenos Aires and might exhort authorities to implement more active sewage surveillance in the region.

Indexed as

ArgentinaBiodiversityEnterovirusEnterovirus InfectionsHigh-Throughput Nucleotide SequencingHumansPhylogenyRetrospective StudiesSewageUrban HealthSewageDeep SequencingEnterovirusEnvironmentHealthSewage

Identifiers

PMID33675515
OpenAlexW3134243824

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.