Evidence map›Paper›PMID 33675407›Full record

SynthesisLangenbeck's archives of surgery2021

Laparoscopic surgery during the COVID-19 pandemic: detection of SARS-COV-2 in abdominal tissues, fluids, and surgical smoke.

Isaac Cheruiyot, Prabjot Sehmi, Brian Ngure, Musa Misiani, Paul Karau, Beda Olabu, Brandon Michael Henry, Giuseppe Lippi, Roberto Cirocchi, Julius Ogeng'o

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Langenbeck's archives of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Surgical smoke and its components, effects, and mitigation: a contemporary review.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. [Impact of COVID-19 on elective and emergency colorectal surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
    Review
  12. Impact of COVID-19 on the outcomes of gastrointestinal surgery.Clinical journal of gastroenterology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Isaac CheruiyotSchool of Medicine, College of Health Sciences, University of Nairobi, Nairobi, Kenya. isaacbmn@outlook.com.ORCID http://orcid.org/0000-0002-1211-8247
Prabjot SehmiSchool of Medicine, College of Health Sciences, University of Nairobi, Nairobi, Kenya.
Brian NgureSchool of Medicine, College of Health Sciences, University of Nairobi, Nairobi, Kenya.
Musa MisianiSchool of Medicine, College of Health Sciences, University of Nairobi, Nairobi, Kenya.
Paul KarauDepartment of Internal Medicine, School of Medicine, Kenya Methodist University, Meru, Kenya.
Beda OlabuSchool of Medicine, College of Health Sciences, University of Nairobi, Nairobi, Kenya.
Brandon Michael HenryCardiac Intensive Care Unit, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Giuseppe LippiSection of Clinical Biochemistry, Department of Neuroscience, Biomedicine and Movement, University of Verona, Verona, Italy.
Roberto CirocchiDepartment of Surgical Science, University of Perugia, Piazza dell'Universitá, 1, 06123, Perugia, PG, Italy.
Julius Ogeng'oSchool of Medicine, College of Health Sciences, University of Nairobi, Nairobi, Kenya.
University of Nairobi · KECincinnati Children's Hospital Medical Center · USKenya Methodist University · KEUniversity of Perugia · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are still concerns over the safety of laparoscopic surgery in coronavirus disease 2019 (COVID-19) patients due to the potential risk of viral transmission through surgical smoke/laparoscopic pneumoperitoneum.

methodsWe performed a systematic review of currently available literature to determine the presence of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) in abdominal tissues or fluids and in surgical smoke.

resultsA total of 19 studies (15 case reports and 4 case series) comprising 29 COVID-19 patients were included. The viral RNA was positively identified in 11 patients (37.9%). The samples that tested positive include the peritoneal fluid, bile, ascitic fluid, peritoneal dialysate, duodenal wall, and appendix. Similar samples, together with the omentum and abdominal subcutaneous fat, tested negative in the other patients. Only one study investigated SARS-COV-2 RNA in surgical smoke generated during laparoscopy, reporting negative findings.

conclusionsThere are conflicting results regarding the presence of SARS-COV-2 in abdominal tissues and fluids. No currently available evidence supports the hypothesis that SARS-COV-2 can be aerosolized and transmitted through surgical smoke. Larger studies are urgently needed to corroborate these findings.

Indexed as

AbdomenAscitic FluidCOVID-19HumansLaparoscopyRNA, ViralSARS-CoV-2SmokeRNA, ViralSmokeCOVID-19SurgerySurgical smoke

Identifiers

PMID33675407
PMCPMC7936592
OpenAlexW3133984000

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.