Evidence map›Paper›PMID 33675366›Full record

ArticleThe Journal of infectious diseases2021

The Association Between Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Post-COVID-19 Syndrome in Healthcare Workers.

Christopher Pereira, Benjamin H L Harris, Matteo Di Giovannantonio, Carolina Rosadas, Charlotte-Eve Short, Rachael Quinlan, Macià Sureda-Vives, Natalia Fernandez, Isaac Day-Weber, Maryam Khan and 8 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Review
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  18. Post‑COVID‑19 syndrome in children (Review).Experimental and therapeutic medicine · 2022
    Review
  19. Post-COVID-19 syndrome and humoral response association after 1 year in vaccinated and unvaccinated patients.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Article
  20. The immunology and immunopathology of COVID-19.Science (New York, N.Y.) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Christopher PereiraCutrale Perioperative and Ageing Group, Department of Bioengineering, Imperial College London, London, United Kingdom.
Benjamin H L HarrisComputational Biology and Integrative Genomics, Department of Oncology, University of Oxford, Oxford, United Kingdom.
Matteo Di GiovannantonioComputational Biology and Integrative Genomics, Department of Oncology, University of Oxford, Oxford, United Kingdom.
Carolina RosadasDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Charlotte-Eve ShortDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Rachael QuinlanDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Macià Sureda-VivesDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Natalia FernandezDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Isaac Day-WeberDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Maryam KhanDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Federica MarchesinDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Ksenia KatsanovskajaDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Eleanor ParkerDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Graham P TaylorDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Richard S TedderDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Myra O McClureDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Melanie DaniCutrale Perioperative and Ageing Group, Department of Bioengineering, Imperial College London, London, United Kingdom.
Michael FertlemanCutrale Perioperative and Ageing Group, Department of Bioengineering, Imperial College London, London, United Kingdom.
Imperial College London · GBThe Wellington Hospital · GBGenomics (United Kingdom) · GB

Funding

Medical Research Council MC_PC_19078
6 · The paper itself

Abstract

It is currently unknown how post-COVID-19 syndrome (PCS) may affect those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This longitudinal study includes healthcare staff who tested positive for SARS-CoV-2 between March and April 2020, with follow-up of their antibody titers and symptoms. More than half (21 of 38) had PCS after 7-8 months. There was no statistically significant difference between initial reverse-transcription polymerase chain reaction titers or serial antibody levels between those who did and those who did not develop PCS. This study highlights the relative commonality of PCS in healthcare workers and this should be considered in vaccination scheduling and workforce planning to allow adequate frontline staffing numbers.

Indexed as

Health PersonnelAdultAgedAnosmiaAntibodies, ViralCohort StudiesCOVID-19FatigueFemaleHeadacheHumansLongitudinal StudiesMaleMiddle AgedNasopharynxRespiratory Tract DiseasesAntibodies, ViralCOVID-19Healthcare workersImperial Hybrid DABALong-COVIDmultidisciplinary teamPost–COVID-19 SyndromeSARS-CoV-2

Identifiers

PMID33675366
PMCPMC7989400
OpenAlexW3134207894

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.