Evidence map›Paper›PMID 33675190›Full record

ArticleJournal of biomedical optics2021

Wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane.

Larissa Heimann, Christopher Carlein, Katharina Sorg, Rolf Diller, Achim Langenbucher, Bernhard Schick, Gentiana Ioana Wenzel

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Larissa HeimannSaarland University, Medical Center, Department of Otolaryngology, Homburg, Germany.
Christopher CarleinUniversity of Kaiserslautern, Department of Physics, Kaiserslautern, Germany.
Katharina SorgSaarland University, Medical Center, Department of Otolaryngology, Homburg, Germany.
Rolf DillerUniversity of Kaiserslautern, Department of Physics, Kaiserslautern, Germany.
Achim LangenbucherSaarland University, Medical Center, Department of Experimental Ophthalmology, Homburg, Germany.
Bernhard SchickSaarland University, Medical Center, Department of Otolaryngology, Homburg, Germany.
Gentiana Ioana WenzelSaarland University, Medical Center, Department of Otolaryngology, Homburg, Germany.
University Medical Center · USSaarland University · DEUniversity of Kaiserslautern · DE

Funding

European Research Council 311469
6 · The paper itself

Abstract

significanceOptoacoustic-induced vibrations of the hearing organ can potentially be used for a hearing device. To increase the efficiency of such a hearing device, the conversion of the light energy into vibration energy within each type of irradiated tissue has to be optimized.

aimTo analyze the wavelength-dependency of optoacoustic-induced vibrations within the tympanic membrane (TM), and to define the most efficient and best-suited optical stimulation parameters for a novel auditory prosthesis. APPROACH: Single nanosecond laser pulses, continuously tunable in a range of visible to near-infrared, were used to excite the guinea pig TM. The induced vibrations of the hearing organ were recorded at the malleus using a laser Doppler vibrometer.

resultsOur results indicate a strong wavelength-dependency of the vibration's amplitude correlating with the superposition of the absorption spectra of the different specific tissue components.

conclusionsWe investigated the spectrum of the vibrations of the hearing organ that were induced optoacoustically within a biological membrane embedded in air, in an animal model. First applications for these results can be envisioned for the optical stimulation of the peripheral hearing organ as well as for research purposes.

Indexed as

Tympanic MembraneVibrationAnimalsGuinea PigsHearingMalleusPhotic Stimulationauditory prostheseshearinglaser Doppler vibrometryoptoacoustictympanic membranevisible/near infrared

Identifiers

PMID33675190
PMCPMC7934890
OpenAlexW3133982606

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.