Evidence map›Paper›PMID 33674943›Full record

ArticleNeurocritical care2021

Effect of Race-Ethnicity and CT Angiography on Renal Injury During Blood Pressure Treatment for Intracerebral Hemorrhage.

Nayna Shah, Sebastian Koch, Zakariya Hassouneh, Antonio Bustillo, Marialaura Simonetto, Kristine O'Phelan, Emma Boslet

Abstract read
PubMed Publisher
In one paragraph

Article in Neurocritical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. The Effects of Race on Acute Kidney Injury.Journal of clinical medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nayna ShahDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, CRB 1365, Miami, FL, 33136, USA.
Sebastian KochDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, CRB 1365, Miami, FL, 33136, USA. skoch@med.miami.edu.ORCID 0000-0003-0244-6033
Zakariya HassounehDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, CRB 1365, Miami, FL, 33136, USA.
Antonio BustilloDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, CRB 1365, Miami, FL, 33136, USA.
Marialaura SimonettoDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, CRB 1365, Miami, FL, 33136, USA.
Kristine O'PhelanDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, CRB 1365, Miami, FL, 33136, USA.
Emma BosletDepartment of Neurology, University of Miami Miller School of Medicine, 1120 NW 14th Street, CRB 1365, Miami, FL, 33136, USA.
University of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLowering blood pressure intensively in acute intracerebral hemorrhage (ICH) is associated with adverse renal events; Blacks and Hispanics have a higher incidence of ICH and kidney disease than Whites. In addition, CT angiography (CTA), which may also be associated with acute kidney injury (AKI), is often done in acute ICH. Our objective was to investigate the relationship between aggressive BP management, CTA, race-ethnicity and the risk of developing AKI in patients presenting with ICH.

methodsWe retrospectively calculated the difference between the highest and lowest systolic blood pressure during the first 24 h of admission in patients with spontaneous ICH over 30 months. Creatinine (Cr) levels at admission were compared to the highest Cr level during the first 7 days after admission. AKI was defined as any > 50% increase of baseline Cr during the first 7 days. Logistic regression models were used to assess the association between race-ethnicity and CTA and AKI. We also analyzed the incidence of AKI stratified by race-ethnicity.

resultsA total of 394 patients were included (mean age ± SD 63 ± 14 years), 160 patients (41%) were women, 162 (41%) Hispanic, 39 (10%) White and 189 (48%) Black. Most of the patients underwent CTA (73%). The prevalence of AKI was (18%), but no difference was found in AKI incidence (19% in Blacks vs. 17% in Whites vs. 18% in Hispanics (p = 0.940). In fully adjusted models, AKI was not associated with race-ethnicity (p = 0.665) or CTA (p = 0.187). The stratified analysis by race-ethnicity did not change our findings.

conclusionWe found no association between race-ethnicity or CTA and AKI during the acute management of ICH in a real-life stroke population. Our findings suggest that CTA can be safely obtained in acute ICH, even in populations of diverse race-ethnicity who may be more prone to adverse kidney events. CTA did not contribute to developing AKI.

Indexed as

Computed Tomography AngiographyEthnicityBlood PressureCerebral HemorrhageFemaleHumansKidneyRetrospective StudiesRisk FactorsBlood pressureComputer tomography angiographyHemorrhageInjuryKidneyRace and ethnicity

Identifiers

PMID33674943
OpenAlexW3134944445

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.