ReviewAnnals of biomedical engineering2021
Advances in the Fabrication of Scaffold and 3D Printing of Biomimetic Bone Graft.
Review in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Candidate Bioinks for Extrusion 3D Bioprinting-A Systematic Review of the Literature.Frontiers in bioengineering and biotechnology · 2021Pooled it
- Structural and Mechanical Durability Evaluation of PLLA Scaffolds for Biomedical Applications.Materials (Basel, Switzerland) · 2026Article
- Evaluation of the Biological Response to Coating 3D-Printed PLA Scaffolds with Coaxial Gelatin-Based Electrospun Fibers.Biomimetics (Basel, Switzerland) · 2026Article
- Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation.Journal of biomedical materials research. Part B, Applied biomaterials · 2026Review
- Effectiveness of the combination of bovine scaffold and autologous calvarial bone dust in burr hole defect closure post-osteoplasty.Surgical neurology international · 2026Article
- Towards a bioengineered airway: advances in tracheal tissue engineering and biofabrication.Frontiers in cell and developmental biology · 2026Review
- Biomimetic Strategies for Bone Regeneration: Smart Scaffolds and Multiscale Cues.Biomimetics (Basel, Switzerland) · 2025Review
- Advances in 3D-Printed Drug Delivery and Screening Platforms for Bone Disease Therapy.Pharmaceutics · 2025Review
- Advancing Bioprinting Technology Utilizing Portable Bioprinters: From Various Device Designs to Dental Applications.Annals of biomedical engineering · 2025Review
- Advances in 3D-printed scaffold technologies for bone defect repair: materials, biomechanics, and clinical prospects.Biomedical engineering online · 2025Review
- From "immune silence" to "immune dialogue": modification strategies for bone substitutes based on bone immunomodulatory characteristics.Frontiers in cell and developmental biology · 2025Review
- 3D cryo-printed hierarchical porous scaffolds provide immobilization of surface-functionalized sleep-inspired small extracellular vesicles: synergistic therapeutic strategies for vascularized bone regeneration based on macrophage phenotype modulation and angiogenesis-osteogenesis coupling.Journal of nanobiotechnology · 2024Article
- Composites of Polylactic Acid with Diatomaceous Earth for 3D-Printing Biocompatible Scaffolds: A Systematic Study of Their Mechanical, Thermal, and Biocompatibility Properties.Bioengineering (Basel, Switzerland) · 2024Article
- A photothermal responsive system accelerating nitric oxide release to enhance bone repair by promoting osteogenesis and angiogenesis.Materials today. Bio · 2024Article
- Advances in Regenerative and Reconstructive Medicine in the Prevention and Treatment of Bone Infections.Biology · 2024Review
- 3D printing technology and its combination with nanotechnology in bone tissue engineering.Biomedical engineering letters · 2024Review
- Review
- 3D-printed bredigite scaffolds with ordered arrangement structures promote bone regeneration by inducing macrophage polarization in onlay grafts.Journal of nanobiotechnology · 2024Article
- A Comprehensive Mechanical Characterization of Subject-Specific 3D Printed Scaffolds Mimicking Trabecular Bone Architecture Biomechanics.Life (Basel, Switzerland) · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The need for bone grafts is tremendous, and that leads to the use of autograft, allograft, and bone graft substitutes. The biology of the bone is quite complex regarding cellular composition and architecture, hence developing a mineralized connective tissue graft is challenging. Traditionally used bone graft substitutes including metals, biomaterial coated metals and biodegradable scaffolds, suffer from persistent limitations. With the advent and rise of additive manufacturing technologies, the future of repairing bone trauma and defects seems to be optimistic. 3D printing has significant advantages, the foremost of all being faster manipulation of various biocompatible materials and live cells or tissues into the complex natural geometries necessary to mimic and stimulate cellular bone growth. The advent of new-generation bioprinters working with high-precision, micro-dispensing and direct digital manufacturing is aiding in ground-breaking organ and tissue printing, including the bone. The future bone replacement for patients holds excellent promise as scientists are moving closer to the generation of better 3D printed bio-bone grafts that will be safer and more effective. This review aims to summarize the advances in scaffold fabrication techniques, emphasizing 3D printing of biomimetic bone grafts.
Indexed as
Identifiers
33674908What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.