ArticleCommunications biology2021
Circadian regulation of night feeding and daytime detoxification in a formidable Asian pest Spodoptera litura.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Functional analysis of down-regulated CYP6AE gene clusters involved in the insecticidal mechanism of lycorine against Spodoptera litura.Pest management science · 2026Article
- Insights on the nutritional ecology of a nocturnal pollinating insect.Insect science · 2026Article
- Review
- Chromosome-level genome assembly of Ctenoplusia agnata and its potential application in Plusiinae pest management.Pest management science · 2025Article
- An integrative strategy used by the aphid Uroleucon formosanum to counter host sesquiterpene lactone defense: Insights from combined genomic and transcriptomic analysis.Insect science · 2025Article
- Artificial night-time lighting and herbivory interactively reduce the biomass production of invasive plants while enhancing that of native plants.Proceedings. Biological sciences · 2025Article
- Adult Diel Locomotor Behaviour in the Agricultural PestInsects · 2025Article
- Oral microbiome is related to lepidopteran herbivore performance by lignin degradation.ISME communications · 2025Article
- Measuring the Flight Trajectory of a Free-Flying Moth on the Basis of Noise-Reduced 3D Point Cloud Time Series Data.Insects · 2024Article
- Regulation of feeding dynamics by the circadian clock, light and sex in an adult nocturnal insect.Frontiers in physiology · 2023Article
- Spatially specific mechanisms and functions of the plant circadian clock.Plant physiology · 2022Review
- Molecular Oscillator Affects Susceptibility of Caterpillars to Insecticides: Studies on the Egyptian Cotton Leaf Worm-Insects · 2022Article
- Circadian and Neuroendocrine Basis of Photoperiodism Controlling Diapause in Insects and Mites: A Review.Frontiers in physiology · 2022Review
- Time of Day-Specific Changes in Metabolic Detoxification and Insecticide Tolerance in the House Fly,Frontiers in physiology · 2021Article
- Insecticidal Terpenes From the Essential Oils ofFrontiers in plant science · 2021Article
- The Circadian Clock in Lepidoptera.Frontiers in physiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Voracious feeding, trans-continental migration and insecticide resistance make Spodoptera litura among the most difficult Asian agricultural pests to control. Larvae exhibit strong circadian behavior, feeding actively at night and hiding in soil during daytime. The daily pattern of larval metabolism was reversed, with higher transcription levels of genes for digestion (amylase, protease, lipase) and detoxification (CYP450s, GSTs, COEs) in daytime than at night. To investigate the control of these processes, we annotated nine essential clock genes and analyzed their transcription patterns, followed by functional analysis of their coupling using siRNA knockdown of interlocked negative feedback system core and repressor genes (SlituClk, SlituBmal1 and SlituCwo). Based on phase relationships and overexpression in cultured cells the controlling mechanism seems to involve direct coupling of the circadian processes to E-boxes in responding promoters. Additional manipulations involving exposure to the neonicotinoid imidacloprid suggested that insecticide application must be based on chronotoxicological considerations for optimal effectiveness.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.