ArticleNature communications2021
Cytotoxic CD8
Open access · goldAbstract read
In one paragraph
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 1 pooled it
17.9field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
137 citing papers in PubMed, 1 synthesis or guideline pooled it, 174 citations in OpenAlex.
- Association between alopecia areata and cardiovascular disease: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Heart-specific T cell responses: from antigens to disease mechanisms.Nature reviews. Cardiology · 2026Review
- Cytomegalovirus Latency Fuels Inflammation Following Myocardial Infarction.Circulation research · 2026Article
- Granzyme B PET Imaging Reveals LgmnAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Cardiac immunity and heart repair: Mechanism, challenge, and future direction.Chinese medical journal · 2026Review
- A pathogenic CD8⁺ TNature communications · 2026Article
- Cardiac regeneration and repair: the emerging mechanisms and therapeutic approaches.Molecular biomedicine · 2026Review
- The bacteroidal metabolite O-LysoPE facilitates hepatocyte-mediated immunosuppression in autoimmune hepatitis.Nature communications · 2026Article
- Necroptosis is a key contributor to impaired cardiac repair following myocardial infarction.Cell death & disease · 2026Article
- The pro-apoptotic GZMB and anti-apoptotic HAX-1 and DAD-1 genes and gene proteins in human right auricular tissue affected by coronary heart disease and aortic valve stenosis: a pilot study.Journal of molecular histology · 2026Article
- The spleen-heart crosstalk in cardiovascular disease: integrating neural, immune, and secretory pathways.Acta pharmacologica Sinica · 2026Review
- Beyond Reperfusion: Early Molecular Drivers and Therapeutic Opportunities in Acute Post-Infarction Cardiac Fibrosis.International journal of molecular sciences · 2026Review
- Modulation of the immunogenic landscape in colorectal cancer by mitochondrial methylation-controlled J protein.Molecular biomedicine · 2026Article
- Review
- NK cells promote cardiac cell death and regulate myelopoiesis in myocardial infarction.Nature communications · 2026Article
- Macrophage Cluster of Differentiation 163 promotes post-infarction cardiac repair and preserves left ventricular function via osteopontin.Clinical and translational medicine · 2026Article
- Activation of α7nAChR prevents maladaptive right ventricular remodeling via inhibiting the recruitment of CCR2Respiratory research · 2026Article
- ILC2-derived IL-9 activates regulatory T cells to facilitate post-myocardial infarction repair.Cell communication and signaling : CCS · 2026Article
- The potential impact of exosomal miR-484 on post-myocardial infarction angiogenesis using bioinformatics and experimental verification.BMC cardiovascular disorders · 2026Article
- Opioids regulate the functional state of immune cells and reduce inflammatory cardiac injury: Role of opioid receptors, MRGPRX2, and TLR4.Journal of biomedical research · 2026Article
77 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
31 authors at 7 institutions in 3 countries.
Icia Santos-ZasUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.ORCID 0000-0002-0310-9074
Jeremie Lemarié *Université de Paris, PARCC, INSERM, F-75015, Paris, France.
Ivana Zlatanova *Université de Paris, PARCC, INSERM, F-75015, Paris, France.
Marine CachanadoAssistance Publique-Hôpitaux de Paris, APHP.SU; Department of Clinical Pharmacology and Clinical Research Platform (URCEST-CRB-CRC-EST), Hôpital Saint Antoine, Paris, France.
Jean-Christophe SeghezziService de cardiologie, Centre Hospitalier de Compiegne, Compiegne, France.
Hakim BenamerService de cardiologie, Institut Cardiovasculaire Paris Sud, Paris, France.
Pascal GoubeService de cardiologie, Centre Hospitalier de Corbeil, Corbeil, France.
Marie VandestienneUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.
Raphael CohenUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.
Maya EzzoUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.
Vincent DuvalUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.
Yujiao ZhangUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.
Jin-Bo SuInserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.ORCID 0000-0002-1823-8928
Alain BizéInserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.
Lucien SambinInserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.
Philippe BonninInserm U965, Department of Physiology, Assistance Publique Hôpitaux de Paris, Hôpital Lariboisière, France.ORCID 0000-0003-3184-3740
Maxime BranchereauInserm U1048-Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), université Paul Sabatier, Toulouse, France.
Christophe HeymesInserm U1048-Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), université Paul Sabatier, Toulouse, France.
Corinne TanchotUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.
José VilarUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.ORCID 0000-0002-9136-7726
Clement DelacroixUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.
Jean-Sebastien HulotUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.
Clement CochainInstitute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany.
Patrick BrunevalUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.
Nicolas DanchinService de cardiologie, Hôpital Europeen G. Pompidou, Assistance Publique, Hôpitaux de Paris, Paris, France.
Alain TedguiUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.ORCID 0000-0002-7229-4875
Ziad MallatUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.
Tabassome SimonAssistance Publique-Hôpitaux de Paris, APHP.SU; Department of Clinical Pharmacology and Clinical Research Platform (URCEST-CRB-CRC-EST), Hôpital Saint Antoine, Paris, France.
Bijan GhalehInserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.ORCID 0000-0003-0061-5462
Jean-Sébastien SilvestreUniversité de Paris, PARCC, INSERM, F-75015, Paris, France.ORCID 0000-0003-3962-2205
Hafid Ait-OufellaUniversité de Paris, PARCC, INSERM, F-75015, Paris, France. hafid.aitoufella@inserm.fr.ORCID 0000-0002-2955-0183
Inserm · FRSorbonne Université · FRUniversité Toulouse III - Paul Sabatier · FRAssistance Publique – Hôpitaux de Paris · FRCentre Hospitalier Compiègne-Noyon · FRInstitut Cardiovasculaire Paris Sud · FRUniversitätsklinikum Würzburg · DE
Funding
British Heart Foundation CH/10/001/27642
Abstract
Acute myocardial infarction is a common condition responsible for heart failure and sudden death. Here, we show that following acute myocardial infarction in mice, CD8
Indexed as
AnimalsApoptosisCD8-Positive T-LymphocytesDisease Models, AnimalFemaleGranzymesHeartHeart FailureHomeodomain ProteinsHumansMaleMiceMice, Inbred C57BLMice, KnockoutMyocardial InfarctionMyocardiumGranzymesGZMB protein, humanGzmb protein, mouseHomeodomain ProteinsRAG-1 protein
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.