ArticleScience (New York, N.Y.)2021
Redox-active antibiotics enhance phosphorus bioavailability.
Article in Science (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 134 citations in OpenAlex.
- Temperature-dependent reprogramming of virulence traits duringbioRxiv : the preprint server for biology · 2026Article
- Genetic regulation of biosynthesis and resistance to redox-active phenazines inMicrobiology spectrum · 2026Article
- Nitric Oxide Tunes Secreted Metabolite Bioactivity.Molecular microbiology · 2026Article
- Desorption of Phosphate from Iron-Bearing Soil Minerals by a Plant Secondary Metabolite.Environmental science & technology · 2026Article
- Gnotobiotic growth and phosphorus limitation of Arabidopsis thaliana and co-occurring microbes on phosphated iron oxides.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Bacteriophage-mediated cell lysis externalizes a metabolically valuable nutrient to broadly modulate bacterial communities.The ISME journal · 2026Article
- Genetically Reprogramming Crops and Rhizobacteria for Nutritional Iron Biofortification.ACS synthetic biology · 2025Review
- Microbial phenazines: biosynthesis, structural diversity, evolution, regulation, and biological significance.Microbiology and molecular biology reviews : MMBR · 2025Review
- Nitric oxide tunes secreted metabolite bioactivity.bioRxiv : the preprint server for biology · 2025Article
- Complete uranium bioreduction in 48 hours: Synergistic electron transfer in a synthetic microbial consortium.Environmental science and ecotechnology · 2025Article
- Phenazines contribute to microbiome dynamics by targeting topoisomerase IV.Nature microbiology · 2025Article
- Multi-omics and field experiments reveal the mechanism of Pseudomonas palleroniana P6 promoting the growth and polyphyllins accumulation in Paris polyphylla.BMC plant biology · 2025Article
- Loss of LasR function leads to decreased repression ofJournal of bacteriology · 2025Article
- Rhythmic radial oxygen loss enhances soil phosphorus bioavailability.Nature communications · 2025Article
- The microbial phosphorus cycle in aquatic ecosystems.Nature reviews. Microbiology · 2025Review
- Sulfur-mediated transformation, export and mineral complexation of organic and inorganic C, N, P and Si in dryland soils.Scientific reports · 2025Article
- The phospho-ferrozine assay: a tool to study bacterial redox-active metabolites produced at the plant root.Applied and environmental microbiology · 2025Article
- A framework for understanding collective microbiome metabolism.Nature microbiology · 2024Review
- Evolution of phosphate scouting in the terrestrial biosphere.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Mineral states and sequestration processes involving soil biogenic components in various soils and desert sands of Inner Mongolia.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Microbial production of antibiotics is common, but our understanding of their roles in the environment is limited. In this study, we explore long-standing observations that microbes increase the production of redox-active antibiotics under phosphorus limitation. The availability of phosphorus, a nutrient required by all life on Earth and essential for agriculture, can be controlled by adsorption to and release from iron minerals by means of redox cycling. Using phenazine antibiotic production by pseudomonads as a case study, we show that phenazines are regulated by phosphorus, solubilize phosphorus through reductive dissolution of iron oxides in the lab and field, and increase phosphorus-limited microbial growth. Phenazines are just one of many examples of phosphorus-regulated antibiotics. Our work suggests a widespread but previously unappreciated role for redox-active antibiotics in phosphorus acquisition and cycling.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.