Evidence map›Paper›PMID 33674429›Full record

ArticleApplied and environmental microbiology2021

Biogenic Amines Increase the Odds of Bacterial Vaginosis and Affect the Growth of and Lactic Acid Production by Vaginal

Joanna-Lynn C Borgogna, Michelle D Shardell, Savannah G Grace, Elisa K Santori, Benjamin Americus, Zhong Li, Alexander Ulanov, Larry Forney, Tiffanie M Nelson, Rebecca M Brotman and 2 more

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Joanna-Lynn C BorgognaDepartment of Animal & Range Sciences, Montana State University, Bozeman, Montana, USA.ORCID 0000-0002-4488-4042
Michelle D ShardellDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Savannah G GraceDepartment of Animal & Range Sciences, Montana State University, Bozeman, Montana, USA.
Elisa K SantoriDepartment of Microbiology & Immunology, Montana State University, Bozeman, Montana, USA.
Benjamin AmericusDepartment of Microbiology & Immunology, Montana State University, Bozeman, Montana, USA.
Zhong LiRoy J. Carver Biotechnology Center, University of Illinois, Urbana, Illinois, USA.
Alexander UlanovRoy J. Carver Biotechnology Center, University of Illinois, Urbana, Illinois, USA.
Larry ForneyInstitute for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, Idaho, USA.ORCID 0000-0003-2448-1219
Tiffanie M NelsonDepartment of Animal & Range Sciences, Montana State University, Bozeman, Montana, USA.
Rebecca M BrotmanDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-8762-6214
Jacques RavelInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-0851-2233
Carl J YeomanDepartment of Animal & Range Sciences, Montana State University, Bozeman, Montana, USA carl.yeoman@montana.edu.ORCID 0000-0002-8775-7879
Montana State University · USUniversity of Maryland, Baltimore · USUniversity of Illinois Urbana-Champaign · USUniversity of Idaho · US

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jeffrey Good · 2012 to 2026
$60.0M
Tracking and Evaluation CoreU54GM115371 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI QUINN, MARK T, RASMUS, STACY M. · 2016 to 2020
$20.9M
Longitudinal Study of the Vaginal Microbiome Prior To Incident STIR01AI116799 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BROTMAN, REBECCA M. · 2015 to 2019
$3.5M
Elucidating causes of vaginal symptoms using a multi-omics approach - Admin. SupplementR01NR015495 · NINR · UNIVERSITY OF MARYLAND BALTIMORE · PI FORNEY, LARRY J, RAVEL, JACQUES · 2016 to 2020
$2.6M
The Microbial Ecology of Bacterial Vaginosis: A Fine Scale Resolution MetagenomicUH2AI083264 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI RAVEL, JACQUES · 2009 to 2011
$1.9M
Microbial Polyamine-Mediated Reductions in Vaginal Acidity; A Mechanistic UnderstR21AI111145 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI WALK, SETH T, YEOMAN, CARL J. · 2014 to 2015
$396k
NIAID NIH HHS R01 AI116799NIAID NIH HHS R21 AI111145NIAID NIH HHS UH2 AI083264NIGMS NIH HHS P20 GM103474NIGMS NIH HHS U54 GM115371NINR NIH HHS R01 NR015495
6 · The paper itself

Abstract

Bacterial vaginosis (BV) is the most common vaginal disorder of reproductive-aged women, yet its etiology remains enigmatic. One clinical symptom of BV, malodor, is linked to the microbial production of biogenic amines (BA). Using targeted liquid chromatography mass spectrometry, we analyzed 149 longitudinally collected vaginal samples to determine the

Indexed as

Biogenic AminesFemaleHumansLactic AcidLactobacillusVaginaVaginosis, BacterialBiogenic AminesLactic Acidbacterial vaginosisbiogenic aminesgrowth responseLactobacillusvaginal microbiome

Identifiers

PMID33674429
PMCPMC8117770
OpenAlexW3133829926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.