Evidence map›Paper›PMID 33674401›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

First-in-Humans Study of the SSTR Antagonist

Richard P Baum, Jingjing Zhang, Christiane Schuchardt, Dirk Müller, Helmut Mäcke

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Targeted βJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Trial
  3. Assessment of the diagnostic efficacy and clinical significance of [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  4. Evaluation of the safety, biodistribution, dosimetry of [European journal of nuclear medicine and molecular imaging · 2024
    Trial
  5. Dosimetry and pharmacokinetics of [European journal of nuclear medicine and molecular imaging · 2024
    Trial
  6. A phase I/II study of the safety and efficacy of [European journal of nuclear medicine and molecular imaging · 2023
    Trial
  7. Development of dual SSTRSC medicinal chemistry · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Practical Aspects ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  17. Article
  18. Review
  19. Article
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Richard P BaumTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Bad Berka, Germany.
Jingjing ZhangTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Bad Berka, Germany; zhangjingjingtag@163.com.
Christiane SchuchardtTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Bad Berka, Germany.
Dirk MüllerTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Bad Berka, Germany.
Helmut MäckeDepartment of Nuclear Medicine, Medical Center, University Hospital of Freiburg, Freiburg, Germany.
Zentralklinik Bad Berka · DEUniversity Medical Center Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to assess the safety, dosimetry, and efficacy of the

Indexed as

Neoplasm MetastasisNeuroendocrine TumorsRadiometryReceptors, SomatostatinAdultAgedFemaleHumansLutetiumMaleMiddle AgedOctreotideOrganometallic CompoundsRadioisotopesSafetyTreatment OutcomeLutetiumLutetium-177OctreotideOrganometallic CompoundsRadioisotopesReceptors, Somatostatin177Lu-DOTA-LM3first-in-humansneuroendocrine neoplasms (NENs)peptide receptor radionuclide therapy (PRRT)SSTR antagonist

Identifiers

PMID33674401
PMCPMC8612334
OpenAlexW3133553083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.