Evidence map›Paper›PMID 33674374›Full record

ArticleBMJ open2021

Description of symptom course in a telemedicine monitoring clinic for acute symptomatic COVID-19: a retrospective cohort study.

James B O'Keefe, Elizabeth J Tong, Ghazala D O'Keefe, David C Tong

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  19. Taste loss as a distinct symptom of COVID-19: A systematic review and meta-analysis.medRxiv : the preprint server for health sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James B O'KeefeDivision of General Internal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA jbokeef@emory.edu.ORCID http://orcid.org/0000-0002-7151-7184
Elizabeth J TongDivision of General Internal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID http://orcid.org/0000-0001-7724-5899
Ghazala D O'KeefeSection of Vitreoretinal Surgery and Diseases, Section of Uveitis and Vasculitis, Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID http://orcid.org/0000-0002-5641-4195
David C TongDivision of Hospital Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID http://orcid.org/0000-0001-9761-6124

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDescribe the disease course in a cohort of outpatients with COVID-19 and evaluate factors predicting duration of symptoms.

designRetrospective cohort study.

settingTelemedicine clinic at a large medical system in Atlanta, Georgia.

participants337 patients with acute COVID-19. Exclusion criteria included intake visit more than 10 days after symptom onset and hospitalisation prior to intake visit.

main outcome measuresSymptom duration in days.

resultsCommon symptoms at intake visit are upper respiratory (73% cough, 55% loss of smell or taste, 57% sinus congestion, 32% sore throat) and systemic (66% headache, 64% body aches, 53% chills, 30% dizziness, 36% fever). Day of symptom onset was earliest for systemic and upper respiratory symptoms (median onset day 1 for both), followed by lower respiratory symptoms (day 3, 95% CI 2 to 4), with later onset of gastrointestinal symptoms (day 4, 95% CI 3 to 5), when present. Cough had the longest duration when present with median 17 days (95% CI 15 to 21), with 42% not resolved at final visit. Loss of smell or taste had the second longest duration with 14 days (95% CI 12 to 17), with 38% not resolved at final visit. Initial symptom severity is a significant predictor of symptom duration (p<0.01 for multiple symptoms).

conclusionsCOVID-19 illness in outpatients follows a pattern of progression from systemic symptoms to lower respiratory symptoms and persistent symptoms are common across categories. Initial symptom severity is a significant predictor of disease duration for most considered symptoms.

Indexed as

TelemedicineAdultAgedCOVID-19FemaleGeorgiaHumansMaleMiddle AgedPregnancyRetrospective StudiesSymptom AssessmentCOVID-19primary caretelemedicine

Identifiers

PMID33674374
PMCPMC7938467

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.