ArticleBMC endocrine disorders2021
The impact of subclinical hypothyroidism on long-term outcomes in older patients undergoing percutaneous coronary intervention.
Article in BMC endocrine disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Short-term outcomes among patients with subclinical hypothyroidism undergoing primary percutaneous coronary intervention.Ghana medical journal · 2023Observational
- Analysis of Subclinical Thyroid Dysfunction and Metabolic Abnormality in 28568 Healthy People.International journal of endocrinology · 2023Article
- Prognostic Value of Normal Thyroid Stimulating Hormone in Long-Term Mortality in Patients With STEMI.Frontiers in endocrinology · 2022Article
- Association of Mild Thyroid Dysfunction and Adverse Prognosis Among Chinese Patients With Acute ST Segment Elevation Myocardial Infarction.Frontiers in endocrinology · 2022Article
- Alterations of Ocular Surface Parameters in Type 2 Diabetic Patients.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSubclinical hypothyroidism (SCH) is reportedly associated with an increased risk of adverse events in patients undergoing percutaneous coronary intervention (PCI). The prognostic significance of SCH in the elderly was poorly defined. The purpose of this study was to evaluate the association between SCH and long-term outcomes in older patients undergoing PCI.
methodsThree thousand one hundred sixty-eight patients aged 65 years or older who underwent PCI from January 2012 to October 2014 were included. Patients were divided into SCH group (n = 320) and euthyroidism (ET) group (n = 2848) based on thyroid function test. Cox proportional hazard regression analyses were used to estimate the relative risks (RRs) of all-cause death and cardiac death for patients with SCH during a 4-year follow-up period.
resultsThere were 227 deaths during the follow-up period including 124 deaths caused by cardiac events. There was no significant difference in mortality rate between the SCH group and the ET group (p > 0.05). After adjustment for covariates, compared with patients with ET, the RRs of death from all-cause and cardiac in patients with SCH were 1.261 (95%CI: 0.802-1.982, p = 0.315) and 1.231 (95%CI: 0.650-2.334, p = 0.524), respectively. When SCH was stratified by age, gender, and degree of thyroid-stimulating hormone elevation, no significant associations were also found in any stratum.
conclusionOur investigation revealed that SCH was negatively associated with the outcome of PCI in older patients.
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