ArticleBMC pregnancy and childbirth2021
Prevalence and clinical, social, and health care predictors of miscarriage.
Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Comparison of Therapist-Guided Versus Self-Guided Internet-Based Stress Inoculation Therapy (ISIT) on Psychological Distress Symptoms in Women After Miscarriage in Iran: A Study Protocol of a Randomized Clinical Trial.Health science reports · 2026Article
- Risk of congenital anomalies among infants of patients with endometriosis: a population-based cohort study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026Article
- Inequities in Care During Pregnancy Loss: Empirical Insights From Experiences With Canadian Perinatal Care.Birth (Berkeley, Calif.) · 2026Article
- Multimodal large language models for women's reproductive mental health.Archives of women's mental health · 2025Review
- Intrauterine application of Budesonide-hyaluronic acid gel in patients with recurrent implantation failure and total loss of junctional zone differentiation on magnetic resonance imaging.Facts, views & vision in ObGyn · 2025Article
- Patient-reported pregnancy loss and maternal complications: Insights from the sickle cell disease implementation consortium.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Article
- Review
- Pregnancy loss and its predictors among ever-pregnant women in Sub-Saharan Africa: Multilevel mixed effect negative binomial regression.PLOS global public health · 2025Article
- Risk factors for first-trimester spontaneous abortion and the role of preconception care.Frontiers in global women's health · 2025Article
- Diagnosis and management of early pregnancy loss.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024Review
- Understanding Miscarriage Prevalence and Risk Factors: Insights from Women in Jordan.Medicina (Kaunas, Lithuania) · 2024Article
- Do women living in a deprived neighborhood have higher maternity care costs and worse pregnancy outcomes? A retrospective population-based study.BMC health services research · 2024Article
- Factors associated with miscarriage in Nepal: Evidence from Nepal Demographic and Health Surveys, 2001-2016.PloS one · 2024Article
- Assessment of Severity of Long QT Syndrome Phenotype and Risk of Fetal Death.Journal of the American Heart Association · 2023Article
- A Retrospective Observational Study Using Administrative Databases to Assess the Risk of Spontaneous Abortions Related to Environmental and Socioeconomic Conditions.Life (Basel, Switzerland) · 2023Article
- Periconceptional antibiotic use and spontaneous abortion: A prospective cohort study.Paediatric and perinatal epidemiology · 2023Article
- Applying Scientific Rationale to the Current Perceptions and Explanations of Massage and Miscarriage in the First Trimester.International journal of therapeutic massage & bodywork · 2023Article
- Initial Impact of Perinatal Loss on Mothers and Their Partners.International journal of environmental research and public health · 2023Article
- Pre-pregnancy migraine diagnosis, medication use, and spontaneous abortion: a prospective cohort study.The journal of headache and pain · 2022Article
- The effects of early pregnancy loss on health outcomes and health care utilization and costs.Health services research · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundPregnancy loss is common and several factors (e.g. chromosomal anomalies, parental age) are known to increase the risk of occurrence. However, much existing research focuses on recurrent loss; comparatively little is known about the predictors of a first miscarriage. Our objective was to estimate the population-level prevalence of miscarriages and to assess the contributions of clinical, social, and health care use factors as predictors of the first detected occurrence of these losses.
methodsIn this population-based cohort study, we used linked administrative health data to estimate annual rates of miscarriage in the Manitoba population from 2003 to 2014, as a share of identified pregnancies. We compared the unadjusted associations between clinical, social, and health care use factors and first detected miscarriage compared with a live birth. We estimated multivariable generalized linear models to assess whether risk factors were associated with first detected miscarriage controlling for other predictors.
resultsWe estimated an average annual miscarriage rate of 11.3%. In our final sample (n = 79,978 women), the fully-adjusted model indicated that use of infertility drugs was associated with a 4 percentage point higher risk of miscarriage (95% CI 0.02, 0.06) and a past suicide attempt with a 3 percentage point higher risk (95% CI -0.002, 0.07). Women with high morbidity were twice as likely to experience a miscarriage compared to women with low morbidity (RD = 0.12, 95% CI 0.09, 0.15). Women on income assistance had a 3 percentage point lower risk (95% CI -0.04, -0.02).
conclusionsWe estimate that 1 in 9 pregnant women in Manitoba experience and seek care for a miscarriage. After adjusting for clinical factors, past health care use and morbidity contribute important additional information about the risk of first detected miscarriage. Social factors may also be informative.
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