Evidence map›Paper›PMID 33673726›Full record

ReviewMaterials (Basel, Switzerland)2021

Biomedical Radioactive Glasses for Brachytherapy.

Francesco Baino, Elisa Fiume, Sara Ciavattini, Saeid Kargozar, Roger Borges, Luis A Genova, Juliana Marchi, Enrica Verné

Open access · goldAbstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Francesco BainoInstitute of Materials Physics and Engineering, Department of Applied Science and Technology (DISAT), Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0001-8860-0497
Elisa FiumeInstitute of Materials Physics and Engineering, Department of Applied Science and Technology (DISAT), Politecnico di Torino, 10129 Torino, Italy.
Sara CiavattiniInstitute of Materials Physics and Engineering, Department of Applied Science and Technology (DISAT), Politecnico di Torino, 10129 Torino, Italy.
Saeid KargozarTissue Engineering Research Group (TERG), Department of Anatomy and Cell Biology, School of Medicine, Mashhad University of Medical Sciences, Mashhad 917794-8564, Iran.
Roger BorgesCentro de Ciências Naturais e Humanas, Universidade Federal do ABC, 09210-580 Santo André, SP, Brazil.
Luis A GenovaCentro de Ciência e Tecnologia dos Materiais, Instituto de Pesquisas Energéticas e Nucleares, 05508-000 Sao Paulo, SP, Brazil.
Juliana MarchiCentro de Ciências Naturais e Humanas, Universidade Federal do ABC, 09210-580 Santo André, SP, Brazil.ORCID 0000-0002-0663-0463
Enrica VernéInstitute of Materials Physics and Engineering, Department of Applied Science and Technology (DISAT), Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0002-8649-4739
Politecnico di Torino · ITUniversidade Federal do ABC · BRInstituto de Pesquisas Energéticas e Nucleares · BRMashhad University of Medical Sciences · IR

Funding

FAPESP Grant no. # 2016-16512-9
6 · The paper itself

Abstract

The fight against cancer is an old challenge for mankind. Apart from surgery and chemotherapy, which are the most common treatments, use of radiation represents a promising, less invasive strategy that can be performed both from the outside or inside the body. The latter approach, also known as brachytherapy, relies on the use of implantable beta-emitting seeds or microspheres for killing cancer cells. A set of radioactive glasses have been developed for this purpose but their clinical use is still mainly limited to liver cancer. This review paper provides a picture of the biomedical glasses developed and experimented for brachytherapy so far, focusing the discussion on the production methods and current limitations of the available options to their diffusion in clinical practice. Highly-durable neutron-activatable glasses in the yttria-alumina-silica oxide system are typically preferred in order to avoid the potentially-dangerous release of radioisotopes, while the compositional design of degradable glass systems suitable for use in radiotherapy still remains a challenge and would deserve further investigation in the near future.

Indexed as

bioactive glassescancer treatmentdurable glassesmicrospheresradioactiveradioisotope

Identifiers

PMID33673726
PMCPMC7957637
OpenAlexW3134549788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.