Evidence map›Paper›PMID 33673662›Full record

ArticleInternational journal of molecular sciences2021

Hopping and Flipping of RNA Polymerase on DNA during Recycling for Reinitiation after Intrinsic Termination in Bacterial Transcription.

Wooyoung Kang, Seungha Hwang, Jin Young Kang, Changwon Kang, Sungchul Hohng

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. RNA polymerase sliding on DNA can couple the transcription of nearby bacterial operons.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Recycling of bacterial RNA polymerase by the Swi2/Snf2 ATPase RapA.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Article
  9. Recycling of Bacterial RNA Polymerase by the Swi2/Snf2 ATPase RapA.bioRxiv : the preprint server for biology · 2023
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wooyoung KangDepartment of Physics and Astronomy, and Institute of Applied Physics, Seoul National University, Seoul 08826, Korea.
Seungha HwangDepartment of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.
Jin Young KangDepartment of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.ORCID 0000-0002-8493-7890
Changwon KangDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.ORCID 0000-0002-0867-6385
Sungchul HohngDepartment of Physics and Astronomy, and Institute of Applied Physics, Seoul National University, Seoul 08826, Korea.ORCID 0000-0002-7131-2138
Korea Advanced Institute of Science and Technology · KRSeoul National University · KR

Funding

KAIST N10110078National Research Foundation of Korea 2019M3E5D6066058National Research Foundation of Korea 2019R1A2C2005209
6 · The paper itself

Abstract

Two different molecular mechanisms, sliding and hopping, are employed by DNA-binding proteins for their one-dimensional facilitated diffusion on nonspecific DNA regions until reaching their specific target sequences. While it has been controversial whether RNA polymerases (RNAPs) use one-dimensional diffusion in targeting their promoters for transcription initiation, two recent single-molecule studies discovered that post-terminational RNAPs use one-dimensional diffusion for their reinitiation on the same DNA molecules.

Indexed as

Gene Expression Regulation, BacterialTranscription Initiation, GeneticTranscription Termination, GeneticDNA, BacterialDNA-Directed RNA PolymerasesEscherichia coliEscherichia coli ProteinsPromoter Regions, GeneticDNA, BacterialDNA-Directed RNA PolymerasesEscherichia coli ProteinsCy3Cy5Escherichia colifluorescent labelingfluorescent transcription complexone-dimensional facilitated diffusionprotein-induced fluorescence enhancementsingle-molecule fluorescencetranscription termination

Identifiers

PMID33673662
PMCPMC7957599
OpenAlexW3134084451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.