Evidence map›Paper›PMID 33673661›Full record

ReviewCancers2021

Clinical and Molecular Characteristics and Outcome of Cystic Partially Differentiated Nephroblastoma and Cystic Nephroma: A Narrative Review of the Literature.

Sophie E van Peer, Corine J H Pleijte, Ronald R de Krijger, Marjolijn C J Jongmans, Roland P Kuiper, Marc R Lilien, Martine van Grotel, Norbert Graf, Marry M van den Heuvel-Eibrink, Janna A Hol

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. The Histological Spectrum of DICER1-Associated Neoplasms.Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Sophie E van PeerPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Corine J H PleijtePrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Ronald R de KrijgerPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Marjolijn C J JongmansPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Roland P KuiperPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.ORCID 0000-0003-4928-3809
Marc R LilienDepartment of Pediatric Nephrology, Wilhelmina Children's Hospital, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Martine van GrotelPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.ORCID 0000-0002-8849-8573
Norbert GrafDepartment of Pediatric Oncology & Hematology, Saarland University Medical Center and Saarland University Faculty of Medicine, D-66421 Homburg, Germany.ORCID 0000-0002-2248-323X
Marry M van den Heuvel-EibrinkPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Janna A HolPrincess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
Princess Máxima Center · NLUniversity Medical Center Utrecht · NLSaarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In children presenting with a predominantly cystic renal tumor, the most likely diagnoses include cystic partially differentiated nephroblastoma (CPDN) and cystic nephroma (CN). Both entities are rare and limited information on the clinical and molecular characteristics, treatment, and outcome is available since large cohort studies are lacking. We performed an extensive literature review, in which we identified 113 CPDN and 167 CN. The median age at presentation for CPDN and CN was 12 months (range: 3 weeks-4 years) and 16 months (prenatal diagnosis-16 years), respectively. No patients presented with metastatic disease. Bilateral disease occurred in both entities. Surgery was the main treatment for both. Two/113 CPDN patients and 26/167 CN patients had previous, concomitant, or subsequent other tumors. Unlike CPDN, CN was strongly associated with somatic (

Indexed as

CNCPDNcystic nephromacystic partially differentiated nephroblastomapediatricrenal tumor

Identifiers

PMID33673661
PMCPMC7957568
OpenAlexW3135383527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.