Evidence map›Paper›PMID 33673609›Full record

ArticleNutrients2021

High-Intensity Interval Training and α-Linolenic Acid Supplementation Improve DHA Conversion and Increase the Abundance of Gut Mucosa-Associated

Claire Plissonneau, Frederic Capel, Benoit Chassaing, Marine Dupuit, Florie Maillard, Ivan Wawrzyniak, Lydie Combaret, Frederic Dutheil, Monique Etienne, Guillaume Mairesse and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Aerobic exercise regulates gut microbiota profiles and metabolite in the early stage of Alzheimer's disease.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Major Depressive Disorder and Gut Microbiota: Role of Physical Exercise.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Claire PlissonneauLaboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Frederic CapelINRAE, UNH, Unité de Nutrition Humaine, CRNH Auvergne, Université Clermont Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0002-0133-0277
Benoit ChassaingInserm U1016, Team ''Mucosal Microbiota in Chronic Inflammatory Diseases'', CNRS UMR 8104, Université de Paris, 75014 Paris, France.
Marine DupuitLaboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Florie MaillardLaboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Ivan WawrzyniakLMGE, CNRS, Laboratoire Microorganismes: Génome et Environnement, Université Clermont Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0002-5362-6117
Lydie CombaretINRAE, UNH, Unité de Nutrition Humaine, CRNH Auvergne, Université Clermont Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0001-6550-8700
Frederic DutheilCNRS, LaPSCo, Physiological and Psychosocial Stress, University Hospital of Clermont-Ferrand, CHU Clermont-Ferrand, WittyFit, 63000 Clermont-Ferrand, France.
Monique EtienneLaboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Guillaume MairesseValorex, La Messayais, 35210 Combourtillé, France.
Guillaume ChesneauValorex, La Messayais, 35210 Combourtillé, France.
Nicolas BarnichM2iSH, UMR 1071 Inserm/Université d'Auvergne, USC-INRAE 2018, Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0001-9465-7844
Nathalie BoisseauLaboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0003-2835-1163
Université Clermont Auvergne · FRCentre National de la Recherche Scientifique · FRInserm · FR

Funding

Chaire d'Excellence from IdEx Université de Paris ANR-18-IDEX-0001European Research Council (ERC) European Union's Horizon 2020 research and innovation programme (grant agreement No. ERC-2018-StG- 804135)Innovator Award from the Kenneth Rainin Foundation xINRAE (USC-2018)Inserm (UMR 1071)I-SITE project (CAP 2025) of the University of Clermont AuvergneMinistère de la Recherche et de la Technologie Annual grantsUniversity of Clermont Auvergne I-SITE project (CAP 2025)
6 · The paper itself

Abstract

Obesity, a major public health problem, is the consequence of an excess of body fat and biological alterations in the adipose tissue. Our aim was to determine whether high-intensity interval training (HIIT) and/or α-linolenic acid supplementation (to equilibrate the n-6/n-3 polyunsaturated fatty acids (PUFA) ratio) might prevent obesity disorders, particularly by modulating the mucosa-associated microbiota. Wistar rats received a low fat diet (LFD; control) or high fat diet (HFD) for 16 weeks to induce obesity. Then, animals in the HFD group were divided in four groups: HFD (control), HFD + linseed oil (LO), HFD + HIIT, HFD + HIIT + LO. In the HIIT groups, rats ran on a treadmill, 4 days.week

Indexed as

Physical Conditioning, AnimalAdipocytesalpha-Linolenic AcidAnimalsBlood GlucoseBody CompositionDocosahexaenoic AcidsErythrocytesEubacterialesFatty AcidsFatty Acids, VolatileFecesGastrointestinal MicrobiomeGlucose Tolerance TestHigh-Intensity Interval TrainingIntestinal Mucosaalpha-Linolenic AcidBlood GlucoseDocosahexaenoic AcidsFatty AcidsFatty Acids, Volatilebody compositionexerciselinseed oil supplementationmicrobiota

Identifiers

PMID33673609
PMCPMC7997329
OpenAlexW3134419493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.