Evidence map›Paper›PMID 33673573›Full record

ArticleJournal of personalized medicine2021

Targeted Physical Therapy Combined with Spasticity Management Changes Motor Development Trajectory for a 2-Year-Old with Cerebral Palsy.

Corri L Stuyvenberg, Shaaron E Brown, Ketaki Inamdar, Megan Evans, Lin-Ya Hsu, Olivier Rolin, Regina T Harbourne, Sarah Westcott McCoy, Michele A Lobo, Natalie A Koziol and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Corri L StuyvenbergRehabilitation Science Graduate Program, University of Minnesota Medical School, MMC 388, 420 Delaware St. SE, Minneapolis, MN 55455, USA.
Shaaron E BrownDepartment of Physical Therapy, Virginia Commonwealth University Health System, 1300 East Marshall Street, PO Box 980419, Richmond, VA 23298, USA.
Ketaki InamdarRehabilitation and Movement Science Program, College of Health Professions, Virginia Commonwealth University, 900 E. Leigh Street, Richmond, VA 23298, USA.ORCID 0000-0003-2773-7718
Megan EvansCollege of Health Professions, Virginia Commonwealth University, 900 E. Leigh Street, Richmond, VA 23298, USA.
Lin-Ya HsuDepartment of Rehabilitation Medicine, Division of Physical Therapy, University of Washington, 1959 NE Pacific Street, Box 356490, Seattle, WA 98195, USA.
Olivier RolinDepartment of Physical Medicine and Rehabilitation, Virginia Commonwealth University Health Sciences, 1223 E. Marshall Street PO Box 980677, Richmond, VA 23298, USA.
Regina T HarbourneRangos School of Health Sciences, Physical Therapy, Duquesne University, 600 Forbes Ave., Pittsburgh, PA 15282, USA.
Sarah Westcott McCoyDepartment of Rehabilitation Medicine, Division of Physical Therapy, University of Washington, 1959 NE Pacific Street, Box 356490, Seattle, WA 98195, USA.
Michele A LoboDepartment of Physical Therapy and Biomechanics & Movement Science Program, University of Delaware, 540 S. College Ave., Newark, DE 19711, USA.ORCID 0000-0003-2892-7687
Natalie A KoziolNebraska Center for Research on Children, Youth, Families & Schools, University of Nebraska Lincoln, 160 Prem S. Paul Research Center at Whittier School, Lincoln, NE 68583, USA.
Stacey C DusingDivision of Biokinesiology and Physical Therapy, University of Southern California, 1540 E Alcazar Street. CHP 155, Los Angeles, CA 90033, USA.ORCID 0000-0003-3847-3893
Virginia Commonwealth University · USUniversity of Washington · USDuquesne University · USUniversity of Delaware · USUniversity of Minnesota Medical Center · USUniversity of Nebraska–Lincoln · USUniversity of Southern California · US

Funding

Institute of Education Sciences R324A150103
6 · The paper itself

Abstract

Therapies for children with cerebral palsy (CP) often fail to address essential components of early rehabilitation: intensity, child initiation, and an embodied approach. Sitting Together And Reaching To Play (START-Play) addresses these issues while incorporating intensive family involvement to maximize therapeutic dosage. While START-Play was developed and tested on children aged 7-16 months with motor delays, the theoretical construct can be applied to intervention in children of broader ages and skills levels. This study quantifies the impact of a broader START-Play intervention combined with Botulinum toxin-A (BoNT-A) and phenol on the developmental trajectory of a 24 month-old child with bilateral spastic CP. In this AB +1 study, A consisted of multiple baseline assessments with the Gross Motor Function Measure-66 and the Assessment of Problem Solving in Play. The research participant demonstrated a stable baseline during A and changes in response to the combination of BoNT-A/phenol and 12 START-Play sessions during B, surpassing the minimal clinically important difference on the Gross Motor Function Measure-66. The follow-up data point (+1) was completed after a second round of BoNT-A/phenol injections. While the findings suggest the participant improved his gross motor skills with BoNT-A/phenol and START-Play, further research is needed to generalize these findings.

Indexed as

Botulinum toxin-Acerebral palsyearly interventionphenolphysical therapy

Identifiers

PMID33673573
PMCPMC7997196
OpenAlexW3135743983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.