Evidence map›Paper›PMID 33673551›Full record

ArticleInternational journal of molecular sciences2021

Reversal of the Inflammatory Responses in Fabry Patient iPSC-Derived Cardiovascular Endothelial Cells by CRISPR/Cas9-Corrected Mutation.

Hui-Yung Song, Yi-Ping Yang, Yueh Chien, Wei-Yi Lai, Yi-Ying Lin, Shih-Jie Chou, Mong-Lien Wang, Chien-Ying Wang, Hsin-Bang Leu, Wen-Chung Yu and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Zebra-Sphinx: Modeling Sphingolipidoses in Zebrafish.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Genome Editing Tools for Lysosomal Storage Disorders.Advances in experimental medicine and biology · 2023
    Article
  8. Review
  9. Article
  10. Review
  11. Inborn errors of metabolism: Lessons from iPSC models.Reviews in endocrine & metabolic disorders · 2021
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Hui-Yung SongCentral Region Laboratory, Center for Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei 11561, Taiwan.ORCID 0000-0003-3295-1938
Yi-Ping YangDivision of Basic Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Yueh ChienDivision of Basic Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0002-1528-9252
Wei-Yi LaiDivision of Basic Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Yi-Ying LinDivision of Basic Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Shih-Jie ChouDivision of Basic Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Mong-Lien WangDivision of Basic Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0002-4060-9131
Chien-Ying WangDepartment of Internal Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Hsin-Bang LeuInstitute of Pharmacology, National Yang-Ming University, Taipei 11221, Taiwan.
Wen-Chung YuDepartment of Internal Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Chian-Shiu ChienDivision of Basic Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0001-9666-1273
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The late-onset type of Fabry disease (FD) with

Indexed as

Endothelial CellsGene EditingInduced Pluripotent Stem CellsMutationalpha-GalactosidaseCRISPR-Associated Protein 9Fabry DiseaseHumansInflammationPhenotypealpha-GalactosidaseCRISPR-Associated Protein 9CRISPR/Cas9 gene editingFabry diseaseinduced pluripotent stem cellsinflammatory

Identifiers

PMID33673551
PMCPMC7956852
OpenAlexW3134349614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.