Evidence map›Paper›PMID 33673500›Full record

Observational studyNutrients2021

Pediatric Multi-Organ Dysfunction Syndrome: Analysis by an Untargeted "Shotgun" Lipidomic Approach Reveals Low-Abundance Plasma Phospholipids and Dynamic Recovery over 8-Day Period, a Single-Center Observational Study.

Mara L Leimanis-Laurens, Karen Ferguson, Emily Wolfrum, Brian Boville, Dominic Sanfilippo, Todd A Lydic, Jeremy W Prokop, Surender Rajasekaran

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mara L Leimanis-LaurensPediatric Critical Care Unit, Helen DeVos Children's Hospital, 100 Michigan Street NE, Grand Rapids, MI 49503, USA.ORCID 0000-0003-0595-4578
Karen FergusonPediatric Critical Care Unit, Helen DeVos Children's Hospital, 100 Michigan Street NE, Grand Rapids, MI 49503, USA.ORCID 0000-0001-7152-2082
Emily WolfrumVan Andel Institute, Bioinformatics & Biostatistics Core, 333 Bostwick Avenue NE, Grand Rapids, MI 49503, USA.
Brian BovillePediatric Critical Care Unit, Helen DeVos Children's Hospital, 100 Michigan Street NE, Grand Rapids, MI 49503, USA.
Dominic SanfilippoPediatric Critical Care Unit, Helen DeVos Children's Hospital, 100 Michigan Street NE, Grand Rapids, MI 49503, USA.
Todd A LydicDepartment of Physiology, Collaborative Mass Spectrometry Core, 567 Wilson Road, East Lansing, MI 48824, USA.
Jeremy W ProkopDepartment of Pediatric and Human Development, College of Human Medicine, Michigan State University, Life Sciences Bldg. 1355 Bogue Street, East Lansing, MI 48824, USA.
Surender RajasekaranPediatric Critical Care Unit, Helen DeVos Children's Hospital, 100 Michigan Street NE, Grand Rapids, MI 49503, USA.
Helen DeVos Children's Hospital · USMichigan State University · USVan Andel Institute · US

Funding

Helen DeVos Children's Hospital Foundation Grant #R51100881018Spectrum Health Office of Research #R51100431217
6 · The paper itself

Abstract

Lipids are molecules involved in metabolism and inflammation. This study investigates the plasma lipidome for markers of severity and nutritional status in critically ill children. Children with multi-organ dysfunction syndrome (MODS) (

Indexed as

LipidomicsChildCritical IllnessHumansMass SpectrometryMultiple Organ FailurePhospholipidsPhospholipidscritical illnesslipidomicsmulti-organ dysfunction syndromenutritional intakepediatricsphospholipids

Identifiers

PMID33673500
PMCPMC7997359
OpenAlexW3134912052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.