Evidence map›Paper›PMID 33673498›Full record

ArticleInternational journal of molecular sciences2021

Peptides from the Intestinal Tract of Breast Milk-Fed Infants Have Antimicrobial and Bifidogenic Activity.

Robert L Beverly, Prajna Woonnimani, Brian P Scottoline, Jiraporn Lueangsakulthai, David C Dallas

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Gut-X axis.iMeta · 2025
    Review
  3. Bioactive milk peptides: an updated comprehensive overview and database.Critical reviews in food science and nutrition · 2024
    Review
  4. Article
  5. Article
  6. Origins, Technological Advancement, and Applications of Peptidomics.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Robert L BeverlyCollege of Public Health and Human Sciences, Oregon State University, Corvallis, OR 97331, USA.ORCID 0000-0002-4838-4600
Prajna WoonnimaniCollege of Agricultural Sciences, Oregon State University, Corvallis, OR 97331, USA.
Brian P ScottolineDivision of Neonatology, School of Medicine, Oregon Health and Science University, Portland, OR 97239, USA.ORCID 0000-0003-0207-9624
Jiraporn LueangsakulthaiCollege of Public Health and Human Sciences, Oregon State University, Corvallis, OR 97331, USA.ORCID 0000-0002-6110-0852
David C DallasCollege of Public Health and Human Sciences, Oregon State University, Corvallis, OR 97331, USA.ORCID 0000-0002-9696-0967
Oregon State University · USOregon Health & Science University · US

Funding

Oregon Clinical and Translational Research Institute TL1 ProgramTL1TR002371 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ALLISON Deborah FRYER, JESSINA C MCGREGOR · 2017 to 2026
$6.2M
Gerber Foundation 2017-1586NIH HHS 1S10OD020111-01NIH HHS 5TL1TR002371-03U.S. Department of Agriculture 2018-67017-27521
6 · The paper itself

Abstract

For bioactive milk peptides to be relevant to infant health, they must be released by gastrointestinal proteolysis and resist further proteolysis until they reach their site of activity. The intestinal tract is the likeliest site for most bioactivities, but it is currently unknown whether bioactive milk peptides are present therein. The purpose of the present study was to identify antimicrobial and bifidogenic peptides in the infant intestinal tract. Milk peptides were extracted from infant intestinal samples, and the activities of the bulk peptide extracts were determined by measuring growth of

Indexed as

Anti-Bacterial AgentsBifidobacterium longum subspecies infantisEscherichia coliHumansInfantIntestinesMilk, HumanPeptidesStaphylococcus aureusAnti-Bacterial AgentsPeptidesantimicrobialbifidogenicbioactive peptideshuman milkinfantsintestinepeptidomics

Identifiers

PMID33673498
PMCPMC7956819
OpenAlexW3133506838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.