Evidence map›Paper›PMID 33673457›Full record

ArticleCancers2021

Renal Cell Carcinoma Health Disparities in Stage and Mortality among American Indians/Alaska Natives and Hispanic Americans: Comparison of National Cancer Database and Arizona Cancer Registry Data.

Celina I Valencia, Samer Asmar, Chiu-Hsieh Hsu, Francine C Gachupin, Ava C Wong, Juan Chipollini, Benjamin R Lee, Ken Batai

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Kidney Cancer Incidence among Non-Hispanic American Indian and Alaska Native Populations in the United States, 1999 to 2020.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Celina I ValenciaCancer Prevention and Control Program, University of Arizona Cancer Center, Tucson, AZ 85724, USA.
Samer AsmarDepartment of Surgery, University of Arizona, Tucson, AZ 85724, USA.
Chiu-Hsieh HsuDepartment of Epidemiology and Biostatistics, University of Arizona, Tucson, AZ 85724, USA.
Francine C GachupinDepartment of Family and Community Medicine, University of Arizona, Tucson, AZ 85724, USA.
Ava C WongDepartment of Urology, University of Arizona, Tucson, AZ 85724, USA.
Juan ChipolliniDepartment of Urology, University of Arizona, Tucson, AZ 85724, USA.
Benjamin R LeeDepartment of Urology, University of Arizona, Tucson, AZ 85724, USA.
Ken BataiDepartment of Urology, University of Arizona, Tucson, AZ 85724, USA.ORCID 0000-0002-0317-1118
University of Arizona · US

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
Uranium as an Environmental Risk Factor for Cancer Among the NavajoU54CA143924 · NCI · UNIVERSITY OF ARIZONA · PI Melissa Marie Herbst-Kralovetz, JUANITA L. MERCHANT · 2009 to 2026
$26.7M
Cancer Prevention and Control Health Disparities Training ProgramT32CA078447 · NCI · UNIVERSITY OF ARIZONA · PI ALBERTS, DAVID SAMUEL, HARRIS, ROBIN B · 2016 to 2020
$1.2M
A Mixed Method to Identify Causes of Kidney Cancer Surgical Disparities in ArizonaR21CA248361 · NCI · UNIVERSITY OF ARIZONA · PI CHIPOLLINI, JUAN · 2020 to 2020
$388k
NCI NIH HHS 1R21CA248361-01NCI NIH HHS P30 CA023074NCI NIH HHS P30CA023074NCI NIH HHS R21 CA248361NCI NIH HHS T32 CA078447NCI NIH HHS T32CA078447NCI NIH HHS U54 CA143924NCI NIH HHS U54CA143924, U54CA143925Urology Care Foundation Research Scholar Award
6 · The paper itself

Abstract

Renal cell carcinoma (RCC) is one of the top 10 cancers in the United States. This study assessed RCC health disparities in American Indians/Alaska Natives (AIs/ANs) and Hispanic Americans (HAs) focusing on advanced-stage and mortality. RCC patients' data were obtained from the National Cancer Database (NCDB) and Arizona Cancer Registry (ACR). Logistic and Cox regression analyses were performed to ascertain the effect of race/ethnicity on stage and mortality, adjusting for neighborhood socioeconomic factors, rural/urban residence pattern, and other factors. In both data sets, AIs/ANs had significantly increased odds of advanced-stage RCC in the unadjusted model, but not in adjusted models. Mexican Americans had higher odds of advanced-stage compared to non-Hispanic Whites in NCDB (OR 1.22, 95% CI: 1.11-1.35) and ACR (OR 2.02, 95% CI: 1.58-2.58), even after adjusting for neighborhood characteristics. AIs/ANs did not show increased mortality risk in NCDB after adjusting for neighborhood characteristics, while the association remained significant in ACR (HR 1.33, 95% CI: 1.03-1.72). The great risk of all-cause and RCC-specific mortality was observed in U.S.-born Mexican Americans in Arizona (HR 3.21, 95% CI: 2.61-3.98 and sub-distribution HR 2.79, 95% CI: 2.05-3.81). RCC disparities in AIs/ANs is partially explained by neighborhood factors, but not in HAs.

Indexed as

cancer health disparitiesgeospatialLatino health paradoxneighborhood effectssocioeconomic status

Identifiers

PMID33673457
PMCPMC7956712
OpenAlexW3134258122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.