Evidence map›Paper›PMID 33673442›Full record

ReviewInternational journal of molecular sciences2021

Synthetic and Bio-Derived Surfactants Versus Microbial Biosurfactants in the Cosmetic Industry: An Overview.

Ana B Moldes, Lorena Rodríguez-López, Myriam Rincón-Fontán, Alejandro López-Prieto, Xanel Vecino, José M Cruz

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Production of Biosurfactant byInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Production and characterization of biosurfactant producing actinobacteria Streptomyces sp. AS1: a sustainable approach for crude oil degradation.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  5. Article
  6. Molecules (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Food science & nutrition · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana B MoldesChemical Engineering Department, School of Industrial Engineering-Cintecx, Campus As Lagoas-Marcosende, University of Vigo, 36310 Vigo, Spain.
Lorena Rodríguez-LópezChemical Engineering Department, School of Industrial Engineering-Cintecx, Campus As Lagoas-Marcosende, University of Vigo, 36310 Vigo, Spain.
Myriam Rincón-FontánChemical Engineering Department, School of Industrial Engineering-Cintecx, Campus As Lagoas-Marcosende, University of Vigo, 36310 Vigo, Spain.
Alejandro López-PrietoChemical Engineering Department, School of Industrial Engineering-Cintecx, Campus As Lagoas-Marcosende, University of Vigo, 36310 Vigo, Spain.ORCID 0000-0002-6829-2762
Xanel VecinoChemical Engineering Department, School of Industrial Engineering-Cintecx, Campus As Lagoas-Marcosende, University of Vigo, 36310 Vigo, Spain.ORCID 0000-0002-5945-7465
José M CruzChemical Engineering Department, School of Industrial Engineering-Cintecx, Campus As Lagoas-Marcosende, University of Vigo, 36310 Vigo, Spain.

Funding

Spanish Ministry of Economy and Competitiveness IJCI-2016-27445Spanish Ministry of Education, Culture and Sport FPU15/00205University of Vigo pre-doctoral fellowshipXunta de Galicia ED431B 2017/77
6 · The paper itself

Abstract

This article includes an updated review of the classification, uses and side effects of surfactants for their application in the cosmetic, personal care and pharmaceutical industries. Based on their origin and composition, surfactants can be divided into three different categories: (i) synthetic surfactants; (ii) bio-based surfactants; and (iii) microbial biosurfactants. The first group is the most widespread and cost-effective. It is composed of surfactants, which are synthetically produced, using non-renewable sources, with a final structure that is different from the natural components of living cells. The second category comprises surfactants of intermediate biocompatibility, usually produced by chemical synthesis but integrating fats, sugars or amino acids obtained from renewable sources into their structure. Finally, the third group of surfactants, designated as microbial biosurfactants, are considered the most biocompatible and eco-friendly, as they are produced by living cells, mostly bacteria and yeasts, without the intermediation of organic synthesis. Based on the information included in this review it would be interesting for cosmetic, personal care and pharmaceutical industries to consider microbial biosurfactants as a group apart from surfactants, needing specific regulations, as they are less toxic and more biocompatible than chemical surfactants having formulations that are more biocompatible and greener.

Indexed as

Surface-Active AgentsBacteriaCosmeticsCosmeticsSurface-Active Agentsbio-based surfactantscosmeticsindustrial applicationmicrobial surfactantspetroleum-based surfactants

Identifiers

PMID33673442
PMCPMC7956807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.