Evidence map›Paper›PMID 33673428›Full record

ArticleMedicina (Kaunas, Lithuania)2021

The Role of Optical Coherence Tomography Angiography (OCTA) in Detecting Choroidal Neovascularization in Different Stages of Best Macular Dystrophy: A Case Series.

Yaqoob Qaseem, Olga German, Maria Vittoria Cicinelli, Rukhsana G Mirza

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Yaqoob QaseemDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60208, USA.
Olga GermanDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60208, USA.
Maria Vittoria CicinelliDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60208, USA.ORCID 0000-0003-2938-0409
Rukhsana G MirzaDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60208, USA.
Northwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Best macular dystrophy (BMD) is an autosomal dominant macular dystrophy of childhood onset characterized by bilateral and symmetric vitelliform lesions. Several stages of disease have been well-described in the literature. Choroidal neovascularization (CNV) has traditionally been considered a hallmark of end-stage disease, and anti-vascular endothelial growth factor (anti-VEGF) agents have been used to improve visual prognosis. While CNV was historically detected with fluorescein angiography, optical coherence tomography angiography (OCTA) has recently been employed as a novel mechanism for identifying CNV in BMD. In this case series, we discuss our institutional experience with using OCTA to detect CNV in BMD and contextualize this experience within the broader emerging literature. While OCTA allows for the identification of CNV in less severe stages of BMD, the management of this CNV remains uncertain.

Indexed as

Choroidal NeovascularizationVitelliform Macular DystrophyFluorescein AngiographyHumansTomography, Optical CoherenceVisual Acuityanti-VEGFBest diseaseBest macular dystrophychoroidal neovascularizationhereditary retinal dystrophies

Identifiers

PMID33673428
PMCPMC7996930
OpenAlexW3134571795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.