Evidence map›Paper›PMID 33673359›Full record

ArticleMicroorganisms2021

Regulatory Control of Rishirilide(s) Biosynthesis in

Olga Tsypik, Roman Makitrynskyy, Xiaohui Yan, Hans-Georg Koch, Thomas Paululat, Andreas Bechthold

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Genetic Engineering ofMicroorganisms · 2021
    Article
  6. Antifungal Activity and Biosynthetic Potential of NewInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Olga TsypikInstitute for Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-Universität, 79104 Freiburg, Germany.
Roman MakitrynskyyInstitute for Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-Universität, 79104 Freiburg, Germany.
Xiaohui YanInstitute for Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-Universität, 79104 Freiburg, Germany.ORCID 0000-0001-7295-8902
Hans-Georg KochFaculty of Medicine, Institute for Biochemistry and Molecular Biology, ZBMZ, Albert-Ludwigs-Universität, 79104 Freiburg, Germany.ORCID 0000-0001-5913-0334
Thomas PaululatDepartment of Chemistry-Biology, Institute of Organic Chemistry II, Universität Siegen, 57068 Siegen, Germany.
Andreas BechtholdInstitute for Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-Universität, 79104 Freiburg, Germany.ORCID 0000-0003-3594-6851
University of Freiburg · DEUniversity of Siegen · DE

Funding

Deutsche Forschungsgemeinschaft 278002225/RTG 2202
6 · The paper itself

Abstract

Streptomycetes are well-known producers of numerous bioactive secondary metabolites widely used in medicine, agriculture, and veterinary. Usually, their genomes encode 20-30 clusters for the biosynthesis of natural products. Generally, the onset and production of these compounds are tightly coordinated at multiple regulatory levels, including cluster-situated transcriptional factors. Rishirilides are biologically active type II polyketides produced by

Indexed as

MarRregulationrishirilideSARPsecondary metabolitesStreptomycestype II polyketide

Identifiers

PMID33673359
PMCPMC7917814
OpenAlexW3132901807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.