Evidence map›Paper›PMID 33673284›Full record

ArticleCancers2021

Prognostic Value of High-Sensitivity Modified Glasgow Prognostic Score in Castration-Resistant Prostate Cancer Patients Who Received Docetaxel.

Keisuke Ando, Shinichi Sakamoto, Shinpei Saito, Maihulan Maimaiti, Yusuke Imamura, Tomokazu Sazuka, Nobuo Sato, Akira Komiya, Naohiko Anzai, Tomohiko Ichikawa

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Keisuke AndoDepartment of Urology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan.
Shinichi SakamotoDepartment of Urology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan.
Shinpei SaitoDepartment of Urology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan.
Maihulan MaimaitiDepartment of Pathology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan.ORCID 0000-0002-3364-1248
Yusuke ImamuraDepartment of Urology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan.
Tomokazu SazukaDepartment of Urology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan.
Nobuo SatoDepartment of Urology, Funabashi Municipal Medical Center, Chiba 273-8588, Japan.
Akira KomiyaDepartment of Urology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan.
Naohiko AnzaiDepartment of Pharmacology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan.
Tomohiko IchikawaDepartment of Urology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan.

Funding

Japan Society for the Promotion of Science 20K09555
6 · The paper itself

Abstract

The Glasgow prognostic score, a marker of systemic inflammation, is associated with clinical outcomes in different cancers including prostate cancer. However, there is no evidence for the relationship between the high-sensitivity modified Glasgow prognostic score (Hs-mGPS) in prostate cancer and its prognosis. This study aimed to investigate the prognostic significance of Hs-mGPS in castration-resistant prostate cancer (CRPC) treated with docetaxel. We retrospectively analyzed clinical datasets from 131 CRPC patients who received docetaxel treatment at Chiba University Hospital and a related hospital. Clinical factors including Hs-mGPS before docetaxel treatment were evaluated according to overall survival. The numbers of patients with Hs-mGPS of 0, 1, and 2 were 88, 30, and 13, respectively. The median prostate-specific antigen (PSA) level was 28.9 ng/mL. The median testosterone level was 13.0 ng/dL. The percentages of bone and visceral metastases were 80.8% and 10.2%, respectively. For overall survival, Hs-mGPS ≥ 1 (hazard ratio of 2.41;

Indexed as

castration-resistant prostate cancerGlasgow prognostic scorehigh-sensitivity modified Glasgow prognostic scoreinflammationprostate-specific antigentestosterone

Identifiers

PMID33673284
PMCPMC7918602

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.