Evidence map›Paper›PMID 33673274›Full record

ArticleBiomolecules2021

Chemical and Bioinformatics Analyses of the Anti-Leishmanial and Anti-Oxidant Activities of Hemp Essential Oil.

Luigi Menghini, Claudio Ferrante, Simone Carradori, Marianna D'Antonio, Giustino Orlando, Francesco Cairone, Stefania Cesa, Antonello Filippi, Caterina Fraschetti, Gokhan Zengin and 3 more

Abstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Designed Water Capture in Terpene Synthase Catalysis.Chembiochem : a European journal of chemical biology · 2026
    Article
  4. Review
  5. Review
  6. Finally Freed-Plants (Basel, Switzerland) · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Antibiotics (Basel, Switzerland) · 2023
    Review
  11. Article
  12. Molluskicidal nanoemulsion ofFrontiers in pharmacology · 2023
    Article
  13. Inhibiting Human andTropical medicine and infectious disease · 2022
    Article
  14. Article
  15. Article
  16. The Medicinal Natural Products ofMolecules (Basel, Switzerland) · 2022
    Review
  17. Anti-Interdisciplinary perspectives on infectious diseases · 2022
    Article
  18. Essential Oil ofMolecules (Basel, Switzerland) · 2021
    Article
  19. Article
  20. Cannabinoids, Phenolics, Terpenes and Alkaloids ofMolecules (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Luigi MenghiniDepartment of Pharmacy, Università degli Studi "Gabriele d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0002-7346-7395
Claudio FerranteDepartment of Pharmacy, Università degli Studi "Gabriele d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0001-9431-9407
Simone CarradoriDepartment of Pharmacy, Università degli Studi "Gabriele d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0002-8698-9440
Marianna D'AntonioBioinvest S.r.l., Via Filippo Masci, Building 6, 66100 Chieti, Italy.
Giustino OrlandoDepartment of Pharmacy, Università degli Studi "Gabriele d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.
Francesco CaironeDepartment of Drug Chemistry and Technology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-9618-1410
Stefania CesaDepartment of Drug Chemistry and Technology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-8649-0017
Antonello FilippiDepartment of Drug Chemistry and Technology, Sapienza University of Rome, 00185 Rome, Italy.
Caterina FraschettiDepartment of Drug Chemistry and Technology, Sapienza University of Rome, 00185 Rome, Italy.
Gokhan ZenginDepartment of Biology, Science Faculty, Selcuk University, Campus, 42130 Konya, Turkey.ORCID 0000-0001-6548-7823
Gunes AkDepartment of Biology, Science Faculty, Selcuk University, Campus, 42130 Konya, Turkey.
Massimo TacchiniDepartment of Life Sciences and Biotechnology (SVeB), UR7 Terra&Acqua Tech, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-7958-355X
Kashif IqbalDepartment of Pharmacy, University of Lahore, Islamabad Campus, Islamabad 54590, Pakistan.ORCID 0000-0003-2758-7094

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Industrial hemp is a multiuse crop that has been widely cultivated to produce fibers and nutrients. The capability of the essential oil (EO) from inflorescences as antimicrobial agent has been reported. However, literature data are still lacking about the hemp EO antiprotozoal efficacy in vivo. The present study aims to unravel this concern through the evaluation of the efficacy of hemp EOs (2.5 mL/kg, intraperitoneally) of three different cultivars, namely

Indexed as

Computational BiologyAnimalsAntioxidantsAntiprotozoal AgentsCannabisGas Chromatography-Mass SpectrometryLeishmaniaMiceOils, VolatilePlant ExtractsAntioxidantsAntiprotozoal Agentshempseed oilOils, VolatilePlant ExtractsbioinformaticsCannabis sativa L.essential oilGC-MS analysisin vivo studiesLeishmania tropicascavenging/reducing activity

Identifiers

PMID33673274
PMCPMC7917915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.