Evidence map›Paper›PMID 33673238›Full record

ArticlePlants (Basel, Switzerland)2021

Antiinflammatory Medicinal Plants from the Ugandan Greater Mpigi Region Act as Potent Inhibitors in the COX-2/PGH

Fabien Schultz, Ogechi Favour Osuji, Barbara Wack, Godwin Anywar, Leif-Alexander Garbe

Open access · goldAbstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Molecules (Basel, Switzerland) · 2023
    Pooled it
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  7. Review
  8. Antitumor Activity ofNutrients · 2025
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Fabien SchultzInstitute of Biotechnology, Faculty III-Process Sciences, Technical University of Berlin, Gustav-Meyer-Allee 25, 13355 Berlin, Germany.ORCID 0000-0003-1904-2430
Ogechi Favour OsujiDepartment of Agriculture and Food Sciences, Neubrandenburg University of Applied Sciences, Brodaer Str. 2, 17033 Neubrandenburg, Germany.
Barbara WackDepartment of Agriculture and Food Sciences, Neubrandenburg University of Applied Sciences, Brodaer Str. 2, 17033 Neubrandenburg, Germany.
Godwin AnywarDepartment of Plant Sciences, Microbiology and Biotechnology, Makerere University, P.O. Box 7062 Kampala, Uganda.ORCID 0000-0003-0926-1832
Leif-Alexander GarbeDepartment of Agriculture and Food Sciences, Neubrandenburg University of Applied Sciences, Brodaer Str. 2, 17033 Neubrandenburg, Germany.
Neubrandenburg University of Applied Sciences · DEMakerere University · UG

Funding

Bundesministerium für Bildung und Forschung 13FH026IX5Bundesministerium für Bildung und Forschung 13FH066PX5Deutsche Forschungsgemeinschaft 414051096
6 · The paper itself

Abstract

Our study investigates 16 medicinal plants via assessment of inhibition of proinflammatory enzymes such as cyclooxygenases (COX). The plants are used by traditional healers in the Greater Mpigi region in Uganda to treat inflammation and related disorders. We present results of diverse in vitro experiments performed with 76 different plant extracts, namely, (1) selective COX-2 and COX-1 inhibitor screening; (2) 15-LOX inhibition screening; (3) antibacterial resazurin assay against multidrug-resistant

Indexed as

Albizia coriariaantibioticsCassine buchananiiCombretum mollecyclooxygenaseErythrina abyssinicaethnopharmacologyfeverFicus saussureanaHarungana madagascariensisinflammationLeucas calostachyslipoxygenaseMicrogramma lycopodioidesMorella kandtianapainPlectranthus hadiensisSecuridaca longipedunculataSesamum calycinum subsp. angustifoliumSolanum aculeastrumToddalia asiaticatraditional medicineWarburgia ugandensisZanthoxylum chalybeum

Identifiers

PMID33673238
PMCPMC7918315
OpenAlexW3132923393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.