Evidence map›Paper›PMID 33673235›Full record

ArticleToxins2021

Extracts Prepared from a Canadian Toxic Plant Induce Light-Dependent Perinuclear Vacuoles in Human Cells.

Jan M Tuescher, Chad R Beck, Locke Spencer, Benjamin Yeremy, Yutong Shi, Raymond J Andersen, Roy M Golsteyn

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jan M TuescherNatural Product and Cancer Cell Laboratories, University of Lethbridge, Lethbridge, AB T1K 3M4, Canada.
Chad R BeckNatural Product and Cancer Cell Laboratories, University of Lethbridge, Lethbridge, AB T1K 3M4, Canada.
Locke SpencerDepartment of Physics and Astronomy, University of Lethbridge, Lethbridge AB T1K 3M4, Canada.ORCID 0000-0002-9941-2077
Benjamin YeremyDepartment of Earth, Ocean, Atmospheric Sciences, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.ORCID 0000-0001-7860-219X
Yutong ShiDepartment of Earth, Ocean, Atmospheric Sciences, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Raymond J AndersenDepartment of Earth, Ocean, Atmospheric Sciences, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Roy M GolsteynNatural Product and Cancer Cell Laboratories, University of Lethbridge, Lethbridge, AB T1K 3M4, Canada.ORCID 0000-0002-0251-7025
University of Lethbridge · CAUniversity of British Columbia · CA

Funding

Canada Foundation for Innovation 34542Natural Sciences and Engineering Research Council of Canada 2017-04398
6 · The paper itself

Abstract

We are investigating plant species from the Canadian prairie ecological zone by phenotypic cell assays to discover toxins of biological interest. We provide the first report of the effects of extracts prepared from the shrub

Indexed as

A549 CellsCell NucleusHT29 CellsHumansLamin Type ALightPlant ExtractsPlants, ToxicSymphoricarposToxins, BiologicalVacuolesLamin Type ALMNA protein, humanPlant ExtractsToxins, BiologicalCanadaCaprifoliaceaelaminopathieslamins A/Cnuclear associated vacuole (NAV), nucleusPelger-Huët AnomalySymphoricarpos occidentalis

Identifiers

PMID33673235
PMCPMC7917763
OpenAlexW3132165990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.