Evidence map›Paper›PMID 33673221›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Predicting Therapeutic Efficacy of Transarterial Chemoembolization with Drug-Eluting Beads for Hepatocellular Carcinoma Using Contrast-Enhanced Ultrasound.

Kazue Shiozawa, Takashi Matsui, Takahiro Murakami, Manabu Watanabe, Iruru Maetani

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kazue ShiozawaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University Ohashi Medical Center 2-22-36, Ohashi, Meguro-ku, Tokyo 153-8515, Japan.
Takashi MatsuiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University Ohashi Medical Center 2-22-36, Ohashi, Meguro-ku, Tokyo 153-8515, Japan.
Takahiro MurakamiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University Ohashi Medical Center 2-22-36, Ohashi, Meguro-ku, Tokyo 153-8515, Japan.
Manabu WatanabeDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University Ohashi Medical Center 2-22-36, Ohashi, Meguro-ku, Tokyo 153-8515, Japan.ORCID 0000-0002-3906-5341
Iruru MaetaniDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University Ohashi Medical Center 2-22-36, Ohashi, Meguro-ku, Tokyo 153-8515, Japan.ORCID 0000-0002-9072-3805
Toho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to assess the usefulness of contrast-enhanced ultrasound (CEUS) for predicting the therapeutic efficacy of transarterial chemoembolization with drug-eluting beads (DEB-TACE) for hepatocellular carcinoma (HCC). Thirty-two patients with HCC who underwent DEB-TACE were enrolled in this study. Enhancement patterns of vascular phase images on CEUS were compared before and within 3 days after DEB-TACE, and the patterns after DEB-TACE were classified as follows: Pattern A, no enhancement; Pattern B, peripheral ring enhancement; Pattern C, partial enhancement within or peripheral to tumors, and Pattern D, reduced or unchanged enhancement in the whole tumor. Enhancement patterns in all lesions and contrast-enhanced computed tomography (CECT) findings after DEB-TACE were compared statistically. The treatment response of DEB-TACE was evaluated using the Modified Response Evaluation Criteria in Solid Tumors (mRECIST) by CECT. The enhancement patterns on CEUS performed within 3 days after DEB-TACE were defined as Pattern A in 17 cases, B in 7, C in 13, and D in 2. The complete response rates at one month after treatment were 94.1% (16/17 lesions) for Pattern A, 85.7% (6/7) for B, 15.4% (2/13) for C, and 50% (1/2) for D. The response rates were significantly higher for lesions with Pattern A compared to those with Pattern C at one month (

Indexed as

contrast-enhanced ultrasoundhepatocellular carcinomaintra-arterial contrast-enhanced ultrasoundtransarterial chemoembolization with drug-eluting beads

Identifiers

PMID33673221
PMCPMC7917690
OpenAlexW3131893076

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.