Evidence map›Paper›PMID 33673204›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Base Excision Repair AP-Endonucleases-Like Genes Modulate DNA Damage Response and Virulence of the Human Pathogen

Rayssa Karla de Medeiros Oliveira, Fabián Andrés Hurtado, Pedro Henrique Gomes, Luiza Lassi Puglia, Fernanda Fonsêca Ferreira, Kunal Ranjan, Patrícia Albuquerque, Márcio José Poças-Fonseca, Ildinete Silva-Pereira, Larissa Fernandes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. DNA damage checkpoint and repair: From the budding yeastComputational and structural biotechnology journal · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Rayssa Karla de Medeiros OliveiraDepartment of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília 70.910-900, Brazil.
Fabián Andrés HurtadoDepartment of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília 70.910-900, Brazil.ORCID 0000-0001-5238-5844
Pedro Henrique GomesDepartment of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília 70.910-900, Brazil.
Luiza Lassi PugliaDepartment of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília 70.910-900, Brazil.
Fernanda Fonsêca FerreiraDepartment of Genetics and Morphology, Institute of Biological Sciences, University of Brasília, Brasília 70.910-900, Brazil.
Kunal RanjanDepartment of Genetics and Morphology, Institute of Biological Sciences, University of Brasília, Brasília 70.910-900, Brazil.ORCID 0000-0001-8764-7373
Patrícia AlbuquerqueFaculty of Ceilândia, University of Brasília, Brasília 72.220-275, Brazil.ORCID 0000-0001-8160-7784
Márcio José Poças-FonsecaDepartment of Genetics and Morphology, Institute of Biological Sciences, University of Brasília, Brasília 70.910-900, Brazil.
Ildinete Silva-PereiraDepartment of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília 70.910-900, Brazil.ORCID 0000-0003-1403-9363
Larissa FernandesFaculty of Ceilândia, University of Brasília, Brasília 72.220-275, Brazil.
Universidade de Brasília · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 431958/2016-5Coordenação de Aperfeiçoamento de Pessoal de Nível Superior PhD fellowship for R. K. M.O.Fundação de Apoio à Pesquisa do Distrito Federal PRONEX 0193.001.200/2016
6 · The paper itself

Abstract

Pathogenic microbes are exposed to a number of potential DNA-damaging stimuli during interaction with the host immune system. Microbial survival in this situation depends on a fine balance between the maintenance of DNA integrity and the adaptability provided by mutations. In this study, we investigated the association of the DNA repair response with the virulence of

Indexed as

AP-endonucleases-like genesAPN1 and APN2base excision repairCryptococcus neoformansvirulence

Identifiers

PMID33673204
PMCPMC7917787
OpenAlexW3133379892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.