Evidence map›Paper›PMID 33673180›Full record

ArticleInternational journal of molecular sciences2021

Suppressive Role of Bam32/DAPP1 in Chemokine-Induced Neutrophil Recruitment.

Li Hao, Aaron J Marshall, Lixin Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Li HaoDepartment of Anatomy, Physiology and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N5E5, Canada.
Aaron J MarshallDepartment of Immunology, University of Manitoba, Winnipeg, MB R3E0T5, Canada.ORCID 0000-0002-1175-5498
Lixin LiuDepartment of Anatomy, Physiology and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N5E5, Canada.
University of Saskatchewan · CAUniversity of Manitoba · CA

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN 06611-2018
6 · The paper itself

Abstract

Bam32 (B cell adaptor molecule of 32 kDa) functions in the immune responses of various leukocytes. However, the role of neutrophil Bam32 in inflammation is entirely unknown. Here, we determined the role of Bam32 in chemokine CXCL2-induced neutrophil chemotaxis in three mouse models of neutrophil recruitment. By using intravital microscopy in the mouse cremaster muscle, we found that transmigrated neutrophil number, neutrophil chemotaxis velocity, and total neutrophil chemotaxis distance were increased in Bam32

Indexed as

Neutrophil InfiltrationSignal TransductionAdaptor Proteins, Signal TransducingAnimalsChemokinesLipoproteinsMiceMice, KnockoutNeutrophilsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktrho GTP-Binding ProteinsAdaptor Proteins, Signal TransducingAkt2 protein, mouseChemokinesDapp1 protein, mouseLipoproteinsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktrho GTP-Binding ProteinsBam32CXCL2neutrophil recruitmentsmall GTPases

Identifiers

PMID33673180
PMCPMC7918626
OpenAlexW3129606693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.