Evidence map›Paper›PMID 33673179›Full record

ArticleViruses2021

A Single Point Mutation, Asn

Kathleen K M Glover, Danica M Sutherland, Terence S Dermody, Kevin M Coombs

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Kathleen K M GloverDepartment of Medical Microbiology and Infectious Diseases, Room 543 Basic Medical Sciences Building, 745 Bannatyne Avenue, University of Manitoba, Winnipeg, MB R3E OJ9, Canada.ORCID 0000-0001-7442-0102
Danica M SutherlandDepartment of Pediatrics, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.
Terence S DermodyDepartment of Pediatrics, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.
Kevin M CoombsDepartment of Medical Microbiology and Infectious Diseases, Room 543 Basic Medical Sciences Building, 745 Bannatyne Avenue, University of Manitoba, Winnipeg, MB R3E OJ9, Canada.ORCID 0000-0001-7667-8430
University of Manitoba · CAUniversity of Pittsburgh · US

Funding

MOLECULAR BASIS OF REOVIRUS PATHOGENESISR01AI038296 · NIAID · VANDERBILT UNIVERSITY · PI DERMODY, TERENCE S. · 1996 to 2019
$3.3M
NIAID NIH HHS R01 AI038296NIH HHS RO1 AI038296
6 · The paper itself

Abstract

Studies of conditionally lethal mutants can help delineate the structure-function relationships of biomolecules. Temperature-sensitive (

Indexed as

Point MutationAmino Acid SubstitutionCapsidCapsid ProteinsHumansMammalian orthoreovirus 3PhenotypeReoviridae InfectionsTemperatureCapsid Proteinsouter-capsid protein σ3reovirus reverse geneticssite-directed mutagenesistemperature-sensitive reovirus

Identifiers

PMID33673179
PMCPMC7917769
OpenAlexW3131888277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.