Evidence map›Paper›PMID 33673007›Full record

ArticleMolecules (Basel, Switzerland)2021

Nopol-Based Quinoline Derivatives as Antiplasmodial Agents.

Rogers J Nyamwihura, Huaisheng Zhang, Jasmine T Collins, Olamide Crown, Ifedayo Victor Ogungbe

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rogers J NyamwihuraDepartment of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS 39217, USA.
Huaisheng ZhangDepartment of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS 39217, USA.
Jasmine T CollinsDepartment of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS 39217, USA.
Olamide CrownDepartment of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS 39217, USA.
Ifedayo Victor OgungbeDepartment of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS 39217, USA.ORCID 0000-0002-8048-5137
Jackson State University · US

Funding

RCMI-Center for Environmental HealthG12MD007581 · NIMHD · JACKSON STATE UNIVERSITY · PI TCHOUNWOU, PAUL B. · 2012 to 2017
$11.2M
Identification, Optimization and Structural Investigation of Antiprotozoal Agents and Molecular TargetSC3GM122629 · NIGMS · JACKSON STATE UNIVERSITY · PI OGUNGBE, IFEDAYO VICTOR · 2017 to 2020
$453k
American Association of University Women naNational Science Foundation HRD-1547836NIGMS NIH HHS SC3 GM122629NIH HHS SC3GM122629; G12MD007581NIMHD NIH HHS G12 MD007581
6 · The paper itself

Abstract

Malaria remains a significant cause of morbidity and mortality in Sub-Saharan Africa and South Asia. While clinical antimalarials are efficacious when administered according to local guidelines, resistance to every class of antimalarials is a persistent problem. There is a constant need for new antimalarial therapeutics that complement parasite control strategies to combat malaria, especially in the tropics. In this work, nopol-based quinoline derivatives were investigated for their inhibitory activity against

Indexed as

AntimalarialsBridged Bicyclo CompoundsHep G2 CellsHumansPlasmodiumQuinolinesAntimalarialsBridged Bicyclo CompoundsnopolQuinolinesaminoquinolinemalarianopolPlasmodium falciparumα-pinene

Identifiers

PMID33673007
PMCPMC7917639
OpenAlexW3129367630

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.