Evidence map›Paper›PMID 33673006›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Role of the Appendicular Skeletal Muscle Index for Predicting the Recurrence-Free Survival of Head and Neck Cancer.

Kun-Yun Yeh, Hang Huong Ling, Shu-Hang Ng, Cheng-Hsu Wang, Pei-Hung Chang, Wen-Chi Chou, Fang-Ping Chen, Yu-Ching Lin

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kun-Yun YehDivision of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Keelung & Chang Gung University, Keelung 222, Taiwan.ORCID 0000-0001-5572-7897
Hang Huong LingDivision of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Keelung & Chang Gung University, Keelung 222, Taiwan.ORCID 0000-0003-4662-1235
Shu-Hang NgDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Linkou & Chang Gung University, Taoyuan City 333, Taiwan.ORCID 0000-0002-1842-6179
Cheng-Hsu WangDivision of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Keelung & Chang Gung University, Keelung 222, Taiwan.
Pei-Hung ChangDivision of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Keelung & Chang Gung University, Keelung 222, Taiwan.ORCID 0000-0002-5006-0277
Wen-Chi ChouDivision of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Linkou & Chang Gung University, Taoyuan City 333, Taiwan.ORCID 0000-0002-0361-4548
Fang-Ping ChenDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital, College of Medicine, Keelung & Chang Gung University, Keelung 222, Taiwan.
Yu-Ching LinOsteoporosis Prevention and Treatment Center, Chang Gung Memorial Hospital, Keelung 222, Taiwan.ORCID 0000-0002-2318-8507
Chang Gung University · TW

Funding

Chang Gang Memorial Hospital CMRPG2E0101-CMRPG2E0103Chang Gang Memorial Hospital CMRPG2J0171Chang Gang Memorial Hospital CORPG2F0011-13Ministry of Science and Technology, Taiwan MOST 108-2314-B-182A-018-MY3
6 · The paper itself

Abstract

backgroundThis study investigates whether the appendicular skeletal muscle index (ASMI) was an independent prognostic predictor for patients with locally advanced head and neck cancer (LAHNC) receiving concurrent chemoradiotherapy (CCRT) and whether there were any differences in lean mass loss in different body regions during CCRT.

methodsIn this prospective study, we analyzed the clinicopathological variables and the total body composition data before and after treatment. The factors associated with the 2-year recurrence-free survival rate (RFSR) were analyzed via logistic regression analysis.

resultsA total of 98 patients were eligible for analysis. The body weight, body mass index, and all parameters of body composition significantly decreased after CCRT. The pretreatment ASMI was the only independent prognostic factor for predicting the 2-year RFSR (hazard ratio, 0.235; 95% confidence interval, 0.062-0.885;

conclusionsThe pretreatment ASMI was the only independent prognostic predictor for the 2-year RFSR of LAHNC patients undergoing CCRT. Asynchronous loss of lean mass may be observed in different body parts after CCRT.

Indexed as

appendicular skeletal muscle indexconcurrent chemoradiotherapydual-energy X-ray absorptiometryhead and neck cancerlean massrecurrence-free survival rate

Identifiers

PMID33673006
PMCPMC7918727
OpenAlexW3132027591

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.