Evidence map›Paper›PMID 33672916›Full record

ArticleMolecules (Basel, Switzerland)2021

Proposed Mechanism for the Antitrypanosomal Activity of Quercetin and Myricetin Isolated from

Farida Larit, Khaled M Elokely, Manal A Nael, Samira Benyahia, Francisco León, Stephen J Cutler, Mohammed M Ghoneim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Plants (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Farida LaritDépartement de Chimie, Faculté des Sciences Exactes, Université des Frères Mentouri Constantine 1, Constantine 25000, Algeria.ORCID 0000-0002-1396-0719
Khaled M ElokelyDepartment of Chemistry, Institute for Computational Molecular Science, Temple University, Philadelphia, PA 19122, USA.ORCID 0000-0002-2394-021X
Manal A NaelDepartment of Chemistry, Institute for Computational Molecular Science, Temple University, Philadelphia, PA 19122, USA.
Samira BenyahiaLaboratoire de Synthèse Organique, Modélisation et Optimisation des Procèdes (LOMOP), Université Badji Mokhtar, Annaba 23000, Algeria.
Francisco LeónDepartment of BioMolecular Sciences, Division of Medicinal Chemistry, University of Mississippi, University, MS 38677, USA.ORCID 0000-0002-5064-2381
Stephen J CutlerDepartment of BioMolecular Sciences, Division of Medicinal Chemistry, University of Mississippi, University, MS 38677, USA.
Mohammed M GhoneimDepartment of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Ad Diriyah, Riyadh 13713, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The in vitro activity of

Indexed as

Models, MolecularAmino Acid SequenceAntiprotozoal AgentsBinding SitesCell DeathConserved SequenceFlavonoidsHypericumLigandsMolecular Dynamics SimulationPhytochemicalsProtein Structure, SecondaryProtozoan ProteinsQuercetinTrypanosomaWaterAntiprotozoal AgentsFlavonoidsLigandsmyricetinPhytochemicalsProtozoan ProteinsQuercetinWaterantileishmanialantitrypanosomaldockingflavonoidshexokinase (TbHK1)Hypericum afrum

Identifiers

PMID33672916
PMCPMC7918497

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.